PHL89664

Forskolin

phyproof^® Reference Substance

• Synonim(y): 7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one, Coleonol, Colforsin
• Wzór empiryczny (zapis Hilla): C₂₂H₃₄O₇
• Numer CAS: 66575-29-9
• Masa cząsteczkowa: 410.50
• NACRES: NA.24
• UNSPSC Code: 41116107
• Beilstein/REAXYS Number: 1692716
• MDL number: MFCD00082317

Właściwości

• grade: primary reference standard
• product line: phyproof^® Reference Substance
• assay: ≥98.0% (HPLC)
• form: crystals
• manufacturer/tradename: PhytoLab
• SMILES string: CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C
• InChI: 1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1
• InChI key: OHCQJHSOBUTRHG-KGGHGJDLSA-N

Opis

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration. Forskolin effects calcium currents and inhibits MAP kinase.

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H312
• Ostrzeżenia: P280 - P302 + P352 + P312 - P362 + P364 - P501
• Hazard Classifications: Acute Tox. 4 Dermal
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3