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U0881

Uric acid

BioXtra, ≥99% (HPLC)

Synonim(y):

2,6,8-Trihydroxypurine

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Do Państwa/SKUDostępnośćCena netto
10 g
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263,00 zł
25 g
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361,00 zł
100 g
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1250,00 zł

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C5H4N4O3
Numer CAS:
Masa cząsteczkowa:
168.11
UNSPSC Code:
12352005
NACRES:
NA.55
PubChem Substance ID:
EC Number:
200-720-7
Beilstein/REAXYS Number:
156158
MDL number:
Assay:
≥99% (HPLC)
Biological source:
animal (seabird feces (guano))
Form:
powder
Solubility:
1 M NaOH: soluble 50 mg/mL, clear, faintly yellow

263,00 zł


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biological source

animal (seabird feces (guano))

Quality Segment

product line

BioXtra

assay

≥99% (HPLC)

form

powder

impurities

≤0.005% Phosphorus (P)

ign. residue

≤0.1%

mp

>300 °C (lit.)

solubility

1 M NaOH: soluble 50 mg/mL, clear, faintly yellow

cation traces

Al: ≤0.005%, Ca: ≤0.01%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.05%, Mg: ≤0.001%, NH4+: ≤0.05%, Na: ≤0.1%, Pb: ≤0.001%, Zn: ≤0.0005%

SMILES string

O=C1NC(=O)C2=C(N1)NC(=O)N2

InChI

1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)

InChI key

LEHOTFFKMJEONL-UHFFFAOYSA-N

General description

Uric acid is the terminal product of purine degradation in humans. It is formed from the action of xanthine oxidase upon xanthine. Elevated levels of uric acid may clinically be manifested as gout. In species other than humans, uric acid can be further metabolized. In mammals other than primates, uric acid is converted to allantoin. In teleost fish, allantoin is further converted to allantoate, which is hydrolyzed to urea and glyoxylate. Uric acid may also be used in the biosynthesis of purines. It has been studied as a scavenger of biological free radicals like peroxynitrite. High-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS) methods for uric acid have been published. Uric acid promotes monocyte chemoattractant protein-1 (MCP-1) expression in vascular smooth muscle cells.

Application

Uric acid has been used:
  • to prepare monosodium urate (MSU) crystals to study its effect on nuclear localization leucine-rich-repeat protein 1 (NLRP1) gene expression
  • as a reductant to test its protective potential against met-myoglobin formation
  • to prepare MSU to study its use as specific ligand of Clec12a.

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U2625U2875NIST913B
Uric acid NIST® SRM® 913b

NIST913B

Uric acid

description

BioXtra, ≥99% (HPLC)

description

≥99%, crystalline

description

-

description

NIST® SRM® 913b

biological source

animal (seabird feces (guano))

biological source

-

biological source

microbial, synthetic

biological source

-

Quality Level

200

Quality Level

100, 200

Quality Level

200

Quality Level

100

assay

≥99% (HPLC)

assay

≥99%

assay

11.0-13.0% anhydrous basis (Sodium, ICP)

assay

-

form

powder

form

crystalline

form

powder

form

crystalline (solid)

solubility

1 M NaOH: soluble 50 mg/mL, clear, faintly yellow

solubility

-

solubility

1 M NaOH: 25 mg/mL, clear, colorless to faintly yellow

solubility

-

cation traces

K: ≤0.05%, NH4+: ≤0.05%, Fe: ≤0.0005%, Pb: ≤0.001%, Mg: ≤0.001%, Cu: ≤0.0005%, Zn: ≤0.0005%, Al: ≤0.005%, Na: ≤0.1%, Ca: ≤0.01%

cation traces

-

cation traces

-

cation traces

-


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Klasa składowania

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Lot/Batch Number

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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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