T9034

Taurocholic acid sodium salt hydrate

BioXtra, ≥95% (HPLC)

• Synonim(y): 2-[(3α,7α,12α-Trihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid, 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide, Sodium taurocholate hydrate
• Wzór empiryczny (zapis Hilla): C₂₆H₄₄NNaO₇S · xH₂O
• Numer CAS: 345909-26-4
• Masa cząsteczkowa: 537.68 (anhydrous basis)
• NACRES: NA.21
• PubChem Substance ID: 24278230
• UNSPSC Code: 12161900
• EC Number: 205-653-7
• MDL number: MFCD00150819

Właściwości

• biological source: synthetic (organic)
• Quality Segment: 200
• description: anionic
• product line: BioXtra
• assay: ≥95% (HPLC)
• form: powder
• mol wt: micellar avg mol wt 2100
• aggregation number: 4
• impurities: ≤0.005% Phosphorus (P), ≤0.1% Insoluble matter
• CMC: 3-11 mM (20-25°C)
• solubility: H₂O: 0.2 M, clear, colorless to faintly yellow
• anion traces: chloride (Cl^-): ≤0.05%, sulfate (SO₄^2-): ≤0.05%
• cation traces: Al: ≤0.0005%, Ca: ≤0.005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.01%, Mg: ≤0.005%, NH₄⁺: ≤0.1%, Pb: ≤0.001%, Zn: ≤0.0005%
• application(s): detection
• functional group: sulfonic acid
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [Na+].[H]O[H].[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@H](CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCS([O-])(=O)=O
• InChI: 1S/C26H45NO7S.Na.H2O/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);;1H2/q;+1;/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;;/m1../s1
• InChI key: RDAJAQDLEFHVNR-NEMAEHQESA-M

Opis

Application

Anionic detergent used for protein solubilization.

Taurocholic acid, a bile acid, may be used in studies of the physiological effects of bile salts on intestinal function and bacterial flora development.

Biochem/physiol Actions

Non-sulfated bile salt, physiological transport substrate for the bile salt export pump/sister of Pgp (BSEP/spgp), Na⁽⁺⁾/taurocholate cotransporter (NTCP) and MRP3 into the hepatic carnalicular.

Non-sulfated bile salt.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)