T0557

Sodium taurodeoxycholate hydrate

BioXtra, ≥97% (TLC)

• Synonim(y): 2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid, Taurodeoxycholic acid sodium salt hydrate
• Wzór liniowy: C₂₆H₄₄NO₆SNa · xH₂O
• Numer CAS: 207737-97-1
• Masa cząsteczkowa: 521.69 (anhydrous basis)
• UNSPSC Code: 12161900
• NACRES: NA.25
• PubChem Substance ID: 24899897
• MDL number: MFCD00149238
• Beilstein/REAXYS Number: 3901204

Właściwości

• description: anionic
• Quality Segment: 200
• product line: BioXtra
• assay: ≥97% (TLC)
• mol wt: micellar avg mol wt 3100
• aggregation number: 6
• impurities: ≤0.002% Phosphorus (P), ≤0.1% Insoluble matter
• CMC: 1-4 mM (20-25°C)
• solubility: H₂O: 0.5 M, clear, colorless to faintly yellow
• anion traces: chloride (Cl^-): ≤0.5%, sulfate (SO₄^2-): ≤0.05%
• cation traces: Al: ≤0.0005%, Ca: ≤0.005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.01%, Mg: ≤0.005%, NH₄⁺: ≤0.05%, Pb: ≤0.001%, Zn: ≤0.0005%
• SMILES string: O.[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
• InChI: 1S/C26H45NO6S.Na.H2O/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3;;/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);;1H2/q;+1;/p-1/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-;;/m1../s1
• InChI key: OLPIZAYYAVQETM-GGPRKOIFSA-M

Opis

General description

Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.

Application

Bile salt-related, anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins.

Sodium tauroursodeoxycholate has been used in a study to assess short-term feedback regulation of bile salt uptake in rodent liver. It has also been used in a study to investigate its potential to resolve endoplasmic reticulum (ER) stress in intestinal epithelial cells. It is also used for isolation of membrane proteins including inner mitochondrial membrane proteins.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)