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T0442

Anti-phospho-Tyk2 (pTyr^1054/1055) antibody produced in rabbit

Name: Anti-phospho-Tyk2 (pTyr<SUP>1054/1055</SUP>) antibody produced in rabbit
Brand: SIGMA
Price: 3670 PLN

affinity isolated antibody, buffered aqueous glycerol solution

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Do Państwa/SKU	Dostępność	Cena netto
0.1 mL	Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności	3670,00 zł

Informacje o tej pozycji

UNSPSC Code:

12352203

NACRES:

NA.44

MDL number:

MFCD02097177

Conjugate:

unconjugated

Clone:

polyclonal

Application:

Citations:

3670,00 zł

Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności

Pomoc techniczna

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Pozwól nam pomóc

Właściwości

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

mol wt

134 kDa

species reactivity

human

technique(s)

western blot: 1:1000

UniProt accession no.

P29597

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr1054/pTyr1055)

Gene Information

human ... TYK2(7297)

Opis

General description

Tyk2 is a member of the Jak family of protein tyrosine kinases. It associates with and is activated by
receptors for many cytokines including IL-13, the IL-6 family, IL-10, and IFN-a and β. Following ligand binding,
Tyk2 is activated by phosphorylation of Tyr1054 and/or Tyr1055. Tyk2 is required for the tyrosine phosphoryla-
tion of Stat3 in the IFN-β signaling cascade.

Immunogen

synthetic phospho-Tyr^1054/1055 peptide corresponding to residues around Tyr^1054/1055 of human Tyk2.

Biochem/physiol Actions

Detects human Tyk2 only when phosphorylated at Tyr^1054/1055.

Physical form

Solution in 10 mM sodium HEPES, pH 7.5, containing 150 mM sodium chloride, 100 μg/ml bovine serum albumin and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Ta pozycja	SAB4300122	WH0007297M1	SAB1411977
Sigma-Aldrich T0442 Anti-phospho-Tyk2 (pTyr^1054/1055) antibody produced in rabbit	Sigma-Aldrich SAB4300122 Anti-phospho-TYK2 (pTyr¹⁰⁵⁴) antibody produced in rabbit	Sigma-Aldrich WH0007297M1 Monoclonal Anti-TYK2 antibody produced in mouse	Sigma-Aldrich SAB1411977 ANTI-TYK2 antibody produced in mouse
description affinity isolated antibody, buffered aqueous glycerol solution	description affinity isolated antibody	description clone 6G12, purified immunoglobulin, buffered aqueous solution	description clone 5A4, purified immunoglobulin, buffered aqueous solution
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form purified immunoglobulin	antibody form purified immunoglobulin
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
Quality Level 200	Quality Level 100	Quality Level 100	Quality Level 100
biological source rabbit	biological source rabbit	biological source mouse	biological source mouse
technique(s) western blot: 1:1000	technique(s) western blot: 1:500-1:1000	technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, immunoprecipitation (IP): suitable, indirect ELISA: suitable, indirect immunofluorescence: suitable, western blot: 1-5 μg/mL	technique(s) immunohistochemistry: suitable, indirect ELISA: suitable, indirect immunofluorescence: suitable, western blot: 1-5 μg/mL
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

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Klasa składowania

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c