SML2088

Procainamide hydrochloride

≥98% (HPLC), powder, sodium channel blocker

• Synonim(y): Procainamide hydrochloride, 4-Amino-N-(2-diethylaminoethyl)benzamide hydrochloride, 4-Aminobenzoic acid 2-diethylaminoethylamide, Amidoprocaine, Amisalin, Cardiorytmin, HC 5006, Novocaine amide hydrochloride, Novocamid hydrochloride, Procainamide monohydrochloride, Procamid, Procamide, Procan SR, Procapan, Procardyl, Pronestyl, Pronestyl hydrochloride, Spicain amide
• Wzór liniowy: H₂NC₆H₄CONHCH₂CH₂N(C₂H₅)₂·HCl
• Numer CAS: 614-39-1
• Masa cząsteczkowa: 271.79
• UNSPSC Code: 12352200
• NACRES: NA.77
• EC Number: 210-381-7
• Beilstein/REAXYS Number: 3729517
• MDL number: MFCD00012998
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Właściwości

• Nazwa produktu: Procainamide hydrochloride, ≥98% (HPLC)
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• mp: 167-169 °C (lit.)
• solubility: H₂O: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: Cl.CCN(CC)CCNC(=O)c1ccc(N)cc1
• InChI: 1S/C13H21N3O.ClH/c1-3-16(4-2)10-9-15-13(17)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3,(H,15,17);1H
• InChI key: ABTXGJFUQRCPNH-UHFFFAOYSA-N
• Gene Information: human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Opis

Application

Procainamide hydrochloride (PAH) is suitable to investigate its binding behavior with human serum albumin[1] and bovine serum albumin by fluorescence quenching study to understand the pharmacokinetic and pharmacodynamic mechanisms of PAH.[1]

Biochem/physiol Actions

Procainamide hydrochloride is a sodium channel blocker and Class IA anti-arrhythmic. It has also been shown to Inhibit DNA methyltransferase and modulate epigenetic regulation of gene expression.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3