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Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C23H31N3O3S · 2HCl
Numer CAS:
Masa cząsteczkowa:
502.50
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥90% (HPLC)
Form:
powder
Storage condition:
desiccated
assay
≥90% (HPLC)
form
powder
storage condition
desiccated
color
white to light brown
solubility
DMSO: 20 mg/mL, clear
shipped in
wet ice
storage temp.
−20°C
SMILES string
SC[C@H](N)CNc1cc(c(cc1)C(=O)N[C@@H](CC(C)C)C(=O)OC)c2ccccc2
InChI key
IENQPUVVSDIXCT-UTKZUKDTSA-N
Biochem/physiol Actions
GGTI-286 is a cell permeable, potent and selective inhibitor of geranylgeranyltransferase I (GGTase I) that selectively disrupts oncogenic K-Ras4B. New study shows that GGTI-286 reduces nuclear localization of β-catenin.
GGTI-286 is a cell permeable, potent and selective inhibitor of geranylgeranyltransferase I (GGTase I). CAAX peptidomimetic.
Other Notes
Air sensitive; dessicant.
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Ta pozycja | |||
|---|---|---|---|
| form powder | form film, lyophilized | form solid (Glassy) | form powder |
| assay ≥90% (HPLC) | assay ≥90% (HPLC) | assay ≥90% (HPLC) | assay ≥98% (HPLC) |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C |
| storage condition desiccated | storage condition - | storage condition OK to freeze | storage condition desiccated |
| solubility DMSO: 20 mg/mL, clear | solubility DMSO: >20 mg/mL | solubility DMSO: 10 mg/mL | solubility DMSO: 2 mg/mL, clear |
| shipped in wet ice | shipped in - | shipped in ambient | shipped in - |
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Klasa składowania
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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