Przejdź do zawartości
Merck

SCP0169

HIV-1 Tat Peptide

≥95% (HPLC), lyophilized powder

HIV-TAT (48-57)
1 of 1 reviewers received a sample product or took part in a promotion
Zaloguj się, aby wyświetlić ceny organizacyjne i kontraktowe.

Wybierz wielkość

1 MG

846,00 zł

846,00 zł


Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności


Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C65H124N34O13
Masa cząsteczkowa:
1589.90
UNSPSC Code:
12352202
NACRES:
NA.32

Przejdź do

Pomoc techniczna
Potrzebujesz pomocy? Nasz zespół doświadczonych naukowców chętnie Ci pomoże.
Pozwól nam pomóc

Nazwa produktu

HIV-TAT (48-57),

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥55%

storage condition

protect from light

storage temp.

−20°C

Porównaj podobne pozycje

Wyświetl pełne porównanie

Pokaż różnice

1 of 4

Ta pozycja
H0292SAB5700590SRP0574
assay

≥95% (HPLC)

assay

-

assay

>95% (HPLC), >95% (SDS-PAGE)

assay

-

form

lyophilized

form

lyophilized powder

form

lyophilized powder

form

frozen liquid

storage condition

protect from light

storage condition

-

storage condition

-

storage condition

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−70°C

composition

Peptide Content, ≥55%

composition

-

composition

-

composition

-

General description

Human immunodeficiency virus (HIV)-transactivator of transcription (Tat), a regulatory protein is coded by the Tat gene of HIV-1. Tat is made up of two exons, highly conserved regions, and subtype-specific regions.[1]

Biochem/physiol Actions

Human immunodeficiency virus (HIV)-transactivator of transcription (Tat) participates in the pathogenesis of HIV-related complications. Tat protein is also involved in HIV-related cardiac dysfunction.[1] HIV-TAT (48-57) is used to facilitate the internalization of synthetic peptides.
Ta strona może zawierać tekst przetłumaczony maszynowo.

Klasa składowania

11 - Combustible Solids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number

Nie widzisz odpowiedniej wersji?

Jeśli potrzebujesz konkretnej wersji, możesz wyszukać konkretny certyfikat według numeru partii lub serii.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Yanan Jiang et al.
Journal of translational medicine, 16(1), 121-121 (2018-05-10)
The human immunodeficiency virus (HIV) is a major global public health issue. HIV-related cardiovascular disease remains a leading cause of morbidity and mortality in HIV positive patients. HIV Tat is a regulatory protein encoded by tat gene of HIV-1, which
S-M Lee et al.
Clinical and experimental immunology, 161(3), 504-511 (2010-07-22)
The immune receptor expressed on myeloid cells 1 (IREM-1) has been known to regulate the activities of myeloid cells through its immunoreceptor tyrosine-based inhibition motifs (ITIMs) in its intracellular region. In order to investigate its effect on macrophage activation, a
S-M Lee et al.
Clinical and experimental immunology, 167(3), 438-446 (2012-02-01)
The immune receptor expressed on myeloid cells 1 (IREM-1/CD300F) has been shown to inhibit various inflammatory processes in myeloid cells, such as macrophages and mast cells. IREM-1 exerts its inhibitory effect through its intracellular immunoreceptor tyrosine-based inhibition motifs (ITIMs). In

Questions

Reviews

Active Filters

    • Review 1
    • Votes 3
    1 out of 5 stars.

    Purchase a different product

    Quite disappointed in this product. For one, they do not provide any information on reconstitution of this lyophilized powder, not even whether to use dH20 or not. Additionally, please look closely at the 3 cited papers that allegedly used this product. One is a review that didn't actually use the product, and the other two are from the same lab that published what looks to be the same experiment twice, but without sufficient methodology. They list that, "Fusion proteins containing ITIMs and HIV-TAT48–57 and its negative control containing only HIV-TAT48–57 were custom-designed and synthesized by Peptron Inc. (Daejeon, Korea)" which is not this product? Additionally, their only methodology in terms of use does not include reconstitution, merely this sentence hidden below a figure, "Cells were pre-treated with 5 µM of TAT, TAT–YADL, TAT–YVTM, TAT–YASL, TAT–YCNM or TAT–YSTI for 30 min before stimulation with 1 µg/ml of lipopolysaccharide (LPS) for 24 h."

    When I contacted a rep about my concerns they said they couldn't help with reconstitution instructions and I should have checked to see if they had instructions before purchasing.... a less than stellar response. Save yourself the time, money, and hassle and find a different product.

    Helpful?

    1. Response from Merck KGaA:

      Thank you for taking the time to leave a review. We are sorry to hear that your experience did not meet expectations. Our Technical Service team has reached out to you with additional resources in effort to resolve this issue. We apologize for any inconvenience this may have caused.

Nasz zespół naukowców ma doświadczenie we wszystkich obszarach badań, w tym w naukach przyrodniczych, materiałoznawstwie, syntezie chemicznej, chromatografii, analityce i wielu innych dziedzinach.

Skontaktuj się z zespołem ds. pomocy technicznej