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SBR00067

Rifampicin Water Soluble

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solubility: 50 mg/mL in water, freely soluble

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Do Państwa/SKUDostępnośćCena netto
50 mg
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378,00 zł

Informacje o tej pozycji

NACRES:
NA.76
UNSPSC Code:
51283601

378,00 zł


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form

solid

Quality Segment

specific activity

(Antibacterial)

sustainability

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solubility

water: freely soluble 50 mg/mL

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria, mycobacteria, viruses

greener alternative category

mode of action

protein synthesis | interferes

storage temp.

−20°C

General description

Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections. Rifampicin is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, and primary biliary cirrhosis (PBC). Rifampicin was also found active by inhibiting Tau Oligomer Propagation in Alzheimer’s disease. In addition, Rifampicin is used as a selection agent for agrobacterium mediated plant transformation.
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Application

Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections. It is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, primary biliary cirrhosis (PBC). It has been shown to cause hepatitis.

Biochem/physiol Actions

Rifampicin inhibits the assembly of DNA and protein into mature virus particles. It inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase, which results in cell death.

Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase. Inhibits the assembly of DNA and protein into mature virus particles.
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Ta pozycja
PHR1664H0396BP1101
description

solubility: 50 mg/mL in water, freely soluble

description

Pharmaceutical Secondary Standard; Certified Reference Material

description

BioReagent, suitable for cell culture

description

British Pharmacopoeia (BP) Reference Standard

antibiotic activity spectrum

Gram-negative bacteria, mycobacteria, Gram-positive bacteria, viruses

antibiotic activity spectrum

-

antibiotic activity spectrum

-

antibiotic activity spectrum

-

mode of action

protein synthesis | interferes

mode of action

-

mode of action

-

mode of action

-

form

solid

form

-

form

crystalline

form

solid

solubility

water: freely soluble 50 mg/mL

solubility

-

solubility

H2O: 400 mg/mL

solubility

water: soluble

storage temp.

−20°C

storage temp.

-10 to -25°C

storage temp.

room temp

storage temp.

2-8°C

sustainability

Greener Alternative Product

sustainability

-

sustainability

-

sustainability

-


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Certyfikaty analizy (CoA)

Lot/Batch Number

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Questions

  1. SBR00067-- I plan to dissolve in water and aliquot in 1 ml amounts. At what temperature should the aliquotes be stored and upto how long it can be stored ( e- -20 C/-70C) After dissolving in water, how long the solution can be stored at -20 C

    1 answer
    1. Solutions prepared at 1 mg/ml may be stored up to 8 weeks at 2 - 8°C or 20°C. This material decomposes rapidly in acidic or alkaline conditions. Solutions are most stable when prepared in degassed water and at neutral pH. Avoid repeated freeze/thaw cycles.

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