This product is slightly soluble in water at < 1mg/mL. Other solvents include DMSO, DMF, and Acetone at approximately 50 mg/mL.
Przejdź do
S6256
Sulfamethazine
99.0-101.0% (on dried basis)
Synonim(y):
4,6-Dimethylsulfadiazine, 4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide, Sulfadimethyldiazine, Sulfadimidine
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| Do Państwa/SKU | Dostępność | Cena netto |
|---|---|---|
25 g | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 236,00 zł |
100 g | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 419,00 zł 356,15 zł |
Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C12H14N4O2S
Numer CAS:
Masa cząsteczkowa:
278.33
UNSPSC Code:
51284910
NACRES:
NA.85
PubChem Substance ID:
EC Number:
200-346-4
Beilstein/REAXYS Number:
261304
MDL number:
236,00 zł
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
Pomoc techniczna
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Pozwól nam pomócQuality Segment
assay
99.0-101.0% (on dried basis)
form
powder or crystals
storage condition
(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
color
white to off-white
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
DNA synthesis | interferes, enzyme | inhibits
storage temp.
2-8°C
SMILES string
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
InChI
1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)
InChI key
ASWVTGNCAZCNNR-UHFFFAOYSA-N
General description
Chemical structure: sulfonamide
Application
Biochem/physiol Actions
An antimicrobial sulfur drug. Induces CYP3A4 expression and acetylated by N-acetyltransferase. Exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11.
Sulfamethazine is an antimicrobial sulfur drug that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfamethazine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid[1]. It induces CYP3A4 expression and is acetylated by N-acetyltransferase. It exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11. Sulfamethazine is bacteriostatic.
Packaging
25G,100G
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
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Ta pozycja | |||
|---|---|---|---|
| mode of action DNA synthesis | interferes, enzyme | inhibits | mode of action DNA synthesis | interferes, enzyme | inhibits | mode of action - | mode of action - |
| antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum - | antibiotic activity spectrum - |
| Quality Level 200 | Quality Level 200 | Quality Level - | Quality Level 300 |
| assay 99.0-101.0% (on dried basis) | assay - | assay - | assay - |
| form powder or crystals | form - | form - | form - |
| storage temp. 2-8°C | storage temp. - | storage temp. - | storage temp. 2-8°C |
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Klasa składowania
11 - Combustible Solids
ppe
Eyeshields, Gloves, type N95 (US)
signalword
Warning
hcodes
Hazard Classifications
Skin Irrit. 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Is Sulfamethazine (Product code: S6256) soluble in water of in any specific solvent. Please suggest.
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