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Merck

S1875

(−)-Scopolamine hydrobromide trihydrate

≥98% (HPLC), muscarinic acetylcholine antagonist, powder

Synonim(y):

Hyoscine hydrobromide, Scopine tropate

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1 G

328,00 zł

5 G

1220,00 zł

25 G

4530,00 zł

328,00 zł

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Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C17H21NO4 · HBr · 3H2O
Numer CAS:
6533-68-2
Masa cząsteczkowa:
438.31
NACRES:
NA.77
PubChem Substance ID:
24277871
UNSPSC Code:
12352116
MDL number:
MFCD00150066
Beilstein/REAXYS Number:
6100669
Assay:
>95% (HPLC)
Form:
powder
Quality level:
200

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Nazwa produktu

(−)-Scopolamine hydrobromide trihydrate, >95% (HPLC), powder

Quality Level

200

assay

>95% (HPLC)

form

powder

optical activity

[α]25/D −23 to −27°, c = 5 in H2O(lit.)

color

white to off-white

mp

195-199 °C (dry matter) (lit.)

solubility

H2O: 50 mg/mL

SMILES string

O.O.O.Br.CN1[C@@H]2C[C@H](C[C@H]1[C@@H]3O[C@H]23)OC(=O)[C@H](CO)c4ccccc4

InChI

1S/C17H21NO4.BrH.3H2O/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;;;;/h2-6,11-16,19H,7-9H2,1H3;1H;3*1H2/t11-,12-,13-,14+,15-,16+;;;;/m1..../s1

InChI key

LACQPOBCQQPVIT-SEYKEWMNSA-N

Gene Information

human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

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Ta pozycja
S7882S8502S0929
(−)-Scopolamine hydrobromide trihydrate >95% (HPLC), powder

Sigma-Aldrich

S1875

(−)-Scopolamine hydrobromide trihydrate

(−)-Scopolamine N-butyl bromide ≥98% (TLC), powder

Sigma-Aldrich

S7882

(−)-Scopolamine N-butyl bromide

(−)-Scopolamine methyl bromide ≥98% (HPLC), powder

Sigma-Aldrich

S8502

(−)-Scopolamine methyl bromide

Scopolamine hydrobromide meets USP testing specifications

Sigma-Aldrich

S0929

Scopolamine hydrobromide

assay

≥98% (HPLC)

assay

≥98% (TLC)

assay

≥98% (HPLC)

assay

-

form

powder

form

powder

form

powder

form

-

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

solubility

H2O: 50 mg/mL

solubility

H2O: 50 mg/mL

solubility

H2O: 50 mg/mL

solubility

-

color

white to off-white

color

white

color

white

color

-

optical activity

[α]25/D −24 to −26°, c = 5 in H2O(lit.)

optical activity

[α]25/D −20.8°, c = 3 in H2O(lit.)

optical activity

[α]25/D −25°, c = 5 in H2O(lit.)

optical activity

-

Biochem/physiol Actions

Competitive nonselective muscarinic acetylcholine antagonist.
Competitive nonselective muscarinic acetylcholine antagonist. Scopolamine-induced amnesia in laboratory animals is a commonly-used model of memory deficit.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

Klasa składowania

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number
0000281204
0000281203
0000281203
0000281204
SLCP6341

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Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Víctor Manuel Torres-García et al.
Psychopharmacology (2024-06-01)
Muscarinic receptor activity in the basolateral amygdala (BLA) is known to be involved in plasticity mechanisms that underlie emotional learning. The BLA is involved in the Attenuation of Neophobia, an incidental taste learning task in which a novel taste becomes
Min-Hee Pang et al.
Neurobiology of learning and memory, 94(2), 206-213 (2010-08-06)
Although cholinergic mechanisms have been widely implicated in learning and memory processes, few studies have investigated the specific contribution of hippocampal cholinergic transmission during trace fear conditioning, a form of associative learning involving a temporal gap between two stimuli. Microinfusions
Silviya Abarova et al.
Biochimica et biophysica acta, 1863(11), 2934-2941 (2017-08-06)
Differential scanning calorimetry was applied to evaluate the efficacy of preventive treatments with biologically active compounds of plant origin against neurodegenerative disorder in mice. As we reported recently, large differences exist between the heat capacity profiles of water-soluble brain proteome
Sitthisak Thongrong et al.
Biomedical reports, 21(3), 130-130 (2024-07-29)
Pinostrobin, a key bioactive compound found in the medicinal plant Boesenbergia rotunda (L.), has been noted for its beneficial biological properties including antioxidant, anti-inflammation, anti-cancer and anti-amnesia activities. In view of this, the present study purposed to evaluate the neuroprotective
David Reiss et al.
Psychopharmacology, 231(22), 4337-4347 (2014-04-29)
Recognition memory is an important aspect of human declarative memory and is one of the routine memory abilities altered in patients with amnestic syndrome and Alzheimer's disease. In rodents, recognition memory has been most widely assessed using the novel object
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Produkty

DISCOVER Bioactive Small Molecules for Neuroscience

DISCOVER Bioactive Small Molecules for Neuroscience

Numer pozycji handlu globalnego

SKUNUMER GTIN
S1875-5G04061836915490
S1875-25G04061832093444
S1875-1G04061836915254

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