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Informacje o tej pozycji
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
4
Pomoc techniczna
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Pozwól nam pomócPomoc techniczna
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Pozwól nam pomócbiological source
goat
Quality Level
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse
concentration
1 mg/mL
technique(s)
immunoprecipitation (IP): 2- 10 μg/mg, western blot: 1:1,000- 1:5,000
accession no.
NP_000928.1
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
human ... POLR2A(5430)
Immunogen
The epitope recognized by PLA0292 maps to a region within the C-terminal repeat of human RNA Polymerase II using the reference sequence NP_000928.1 (GeneID 5430).
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Other Notes
The RNA polymerase II subunit B1 (RPB1) is the largest subunit of the RNA polymerase II core complex. RNA polymerase II holoenzyme functions to transcribe DNA into messenger RNA in eukaryotes. RPB1 forms the DNA binding domain of the polymerase that forms a cleft that grabs the incoming DNA template to translocate the holoenzyme across the RNA-DNA hybrid.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Klasa składowania
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
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Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
James P Wells et al.
PLoS genetics, 18(12), e1010309-e1010309 (2022-12-09)
DNA replication is a vulnerable time for genome stability maintenance. Intrinsic stressors, as well as oncogenic stress, can challenge replication by fostering conflicts with transcription and stabilizing DNA:RNA hybrids. RAD18 is an E3 ubiquitin ligase for PCNA that is involved
Jianfei Zhang et al.
International journal of oral science, 11(2), 12-12 (2019-03-19)
Genetic studies have revealed a critical role of Distal-homeobox (Dlx) genes in bone formation, and our previous study showed that Dlx2 overexpressing in neural crest cells leads to profound abnormalities of the craniofacial tissues. The aim of this study was
Emily Yun-Chia Chang et al.
Nature communications, 10(1), 4265-4265 (2019-09-21)
Ectopic R-loop accumulation causes DNA replication stress and genome instability. To avoid these outcomes, cells possess a range of anti-R-loop mechanisms, including RNaseH that degrades the RNA moiety in R-loops. To comprehensively identify anti-R-loop mechanisms, we performed a genome-wide trigenic
Sangin Kim et al.
Nucleic acids research, 48(13), 7218-7238 (2020-06-17)
R-loops are formed when replicative forks collide with the transcriptional machinery and can cause genomic instability. However, it is unclear how R-loops are regulated at transcription-replication conflict (TRC) sites and how replisome proteins are regulated to prevent R-loop formation or
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| PLA0292-100UL | 04061837723988 |
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