About This Item
Polecane produkty
product name
Protamine from salmon, Grade IV, Histone, free(Millon test)
pochodzenie biologiczne
fish (salmon)
typ
Grade IV
Postać
solid
zanieczyszczenia
Histone, free (Millon test)
rozpuszczalność
H2O: soluble, clear to slightly hazy, colorless to faintly yellow
temp. przechowywania
−20°C
Opis ogólny
Protamines are proteins rich in cysteine and arginine. It possesses many phosphorylation sites. Salmon fish contains around 15 genes encoding protamine. It is found to be localized to the sperm head.
Zastosowanie
Protamine from salmon has been used to avoid in vitro AT complex formation in samples from dogs pre-treated with heparin. It has also been used to study the influences of external potential on adsorption of various proteins to a metal surface.
Działania biochem./fizjol.
Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamines are found to displace histones in DNA during spermatogenesis in animals and plants. Protamine is useful as a heparin neutralizer during heart surgery, dialysis and in many other clinical procedures.
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
Certyfikaty analizy (CoA)
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Klienci oglądali również te produkty
Adsorption characteristics of various proteins on a metal surface in the presence of an external electric potential
Colloids and Surfaces, B: Biointerfaces, 262-268 (2018)
Intravascular inhibition of factor VIIa and the analogue NN1731 by antithrombin
British Journal of Haematology, 152(1), 99-107 (2011)
The protamine family of sperm nuclear proteins
Genome Biology, 8(9), 227-227 (2007)
Nucleic acids research, 48(11), 6108-6119 (2020-05-12)
Protamine proteins dramatically condense DNA in sperm to almost crystalline packing levels. Here, we measure the first step in the in vitro pathway, the folding of DNA into a single loop. Current models for DNA loop formation are one-step, all-or-nothing
Packaging paternal chromosomes with protamine
Nature Genetics, 28(1), 10-10 (2001)
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