O8010

Okadaic acid ammonium salt

From plant (Prorocentrum concavum), ≥90% (HPLC), type 1 and type 2A protein phosphatases inhibitor, solid

• Synonim(y): OA
• Wzór empiryczny (zapis Hilla): C₄₄H₆₈O₁₃ · NH₃
• Numer CAS: 155716-06-6
• Masa cząsteczkowa: 822.03
• UNSPSC Code: 12352106
• PubChem Substance ID: 24898053
• NACRES: NA.77
• MDL number: MFCD00153856
• Assay: ≥90% (HPLC)
• Form: solid
• Quality level: 200

Właściwości

• Nazwa produktu: Okadaic acid ammonium salt from Prorocentrum concavum, ≥90% (HPLC), solid
• biological source: plant (Prorocentrum concavum)
• Quality Level: 200
• assay: ≥90% (HPLC)
• form: solid
• color: white
• solubility: H₂O: 0.1 mg/mL, DMSO: soluble, ethanol: soluble
• storage temp.: −20°C
• SMILES string: [H][N+]([H])([H])[H].[H][C@]1(CC[C@@H](O)[C@@]2(O[C@@H](CC(C)=C2)C(C)\C=C\[C@@]3([H])CC[C@@]4(CCC5O[C@H]([C@@H](O)C[C@H](C)C6O[C@@]7(CCCCO7)CC[C@H]6C)C(=C)[C@@H](O)[C@]5([H])O4)O3)O1)C[C@@](C)(O)C([O-])=O
• InChI: 1S/C44H68O13.H3N/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);1H3/b10-9+;/t26-,27-,28+,30+,31+,32+,33?,34+,35-,36-,37?,38+,39-,41-,42+,43-,44-;/m1./s1

Opis

Biochem/physiol Actions

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.

Okadaic acid is a dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS06
• signalword: Danger
• hcodes: H301 + H311 + H331,H315
• pcodes: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3