O2378

Oxymetazoline hydrochloride

≥99%, α1- and α2-adrenergic and 5-HT1 receptor agonist, solid

• Synonim(y): 2-(3-Hydroxy-2,6-dimethyl-4-t-butylbenzyl)-2-imidazoline hydrochloride
• Wzór empiryczny (zapis Hilla): C₁₆H₂₄N₂O · HCl
• Numer CAS: 2315-02-8
• Masa cząsteczkowa: 296.84
• NACRES: NA.77
• PubChem Substance ID: 24277792
• UNSPSC Code: 12352200
• EC Number: 219-015-0
• MDL number: MFCD00058147
• Assay: ≥99%
• Form: solid

Właściwości

• Nazwa produktu: Oxymetazoline hydrochloride, ≥99%, solid
• Quality Segment: 100
• assay: ≥99%
• form: solid
• solubility: H₂O: soluble, alcohol: soluble
• originator: Schering Plough
• SMILES string: Cl.Cc1cc(c(O)c(C)c1CC2=NCCN2)C(C)(C)C
• InChI: 1S/C16H24N2O.ClH/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14;/h8,19H,6-7,9H2,1-5H3,(H,17,18);1H
• InChI key: BEEDODBODQVSIM-UHFFFAOYSA-N
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), HTR1A(3350), HTR1B(3351), HTR1D(3352)

Opis

Biochem/physiol Actions

Oxymetazoline hydrochloride is a partial α_2A-adrenoceptor agonist; agonist at 5-HT_1A, 5-HT_1B, and 5-HT_1D serotonin receptors. It is a mixed agonist-antagonist at 5-HT_1C serotonin receptors.

Features and Benefits

This compound is featured on the α2-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Schering Plough. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS06,GHS05
• signalword: Danger
• hcodes: H300 + H330,H318,H412
• pcodes: P260 - P264 - P273 - P280 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Chronic 3 - Eye Dam. 1
• Klasa składowania: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3