Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Przejdź do
MAK099
Glutamate Dehydrogenase (GDH) Activity Assay Kit
sufficient for 100 colorimetric tests
Zaloguj się, aby wyświetlić ceny organizacyjne i kontraktowe.
Informacje o tej pozycji
NACRES:
NA.84
UNSPSC Code:
12161503
usage
sufficient for 100 colorimetric tests
detection method
colorimetric
relevant disease(s)
cancer; gastrointestinal diseases
storage temp.
−20°C
Gene Information
human ... GLUD1(2746), GLUD2(2747)
mouse ... GLUD1(14661)
rat ... GLUD1(24399)
General description
Glutamate Dehydrogenase (GDH) is a mitochondrial enzyme that catalyzes the reversible oxidative deamination of glutamate to α-ketoglutarate and serves as a key link between anabolic and catabolic pathways. In mammals, GDH is subject to allosteric regulation and has high activity in liver, kidney, brain, and pancreas. GDH activity in serum can be used to differentiate between liver diseases due to liver inflammation, which do not show elevated serum GDH activity, and diseases that result in hepatocyte necrosis, which results in elevated serum GDH.
Application
Suitable for detecting glutamate dehydrogenase (GDH) activity in serum or tissue and cell extracts.
Glutamate Dehydrogenase (GDH) Activity Assay Kit has been used to determine the enzymatic activity of glutamate dehydrogenase.
Biochem/physiol Actions
GDH activity is determined by a coupled enzyme assay in which glutamate is consumed by GDH generating NADH, which reacts with a probe generating a colorimetric (450 nm) product proportional to the GDH activity present. One unit of GDH is the amount of enzyme that will generate 1.0 μmole of NADH per minute at pH 7.6 at 37 °C.
Features and Benefits
Compatible with high-throughput handling systems.
Ta strona może zawierać tekst przetłumaczony maszynowo.
Klasa składowania
10 - Combustible liquids
Wybierz jedną z najnowszych wersji:
Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Powiązane treści
Instructions
Inactivation of Lsd1 triggers senescence in trophoblast stem cells by induction of Sirt4.
Castex J, et al.
Cell Death & Disease, 8(2), e2631-e2631 (2017)
Is liver enzyme release really associated with cell necrosis induced by oxidant stress?.
Contreras-Zentella M L and Hernandez-Mu?oz R
Oxidative Medicine and Cellular Longevity, 2016 (2016)
Tongxin Wang et al.
Animal nutrition (Zhongguo xu mu shou yi xue hui), 4(3), 329-337 (2018-09-04)
The liver is the most essential organ for the metabolism of ammonia, in where most of ammonia is removed by urea and glutamine synthesis. Regulated by leucine, glutamate dehydrogenase (GDH) catalyzes the reversible inter-conversion of glutamate to ammonia. To determine
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| MAK099-1KT | 04054839595455 |
-
What is the Department of Transportation shipping information for this product?
1 answer-
Helpful?
-