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M5308

Sigma-Aldrich

L-Methionine

L-Methionine

99.0-101.0%, suitable for cell culture, BioXtra, non-animal source

Synonim(y):

(S)-2-Amino-4-(methylmercapto)butyric acid, L-2-Amino-4-(methylthio)butanoic acid

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10 MG
180,00 zł
25 G
418,00 zł
100 G
1300,00 zł
1 KG
6590,00 zł

180,00 zł

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Wszystkie zdjęcia(4)

Wybierz wielkość

Zmień widok
10 MG
180,00 zł
25 G
418,00 zł
100 G
1300,00 zł
1 KG
6590,00 zł

About This Item

Wzór liniowy:
CH3SCH2CH2CH(NH2)CO2H
Numer CAS:
63-68-3
Masa cząsteczkowa:
149.21
Beilstein:
1722294
Numer WE:
200-562-9
Numer MDL:
MFCD00063097
Kod UNSPSC:
12352209
eCl@ss:
32160406
Identyfikator substancji w PubChem:
24896818
NACRES:
NA.26

180,00 zł

Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
Poproś o zamówienie zbiorcze

Nazwa produktu

L-Methionine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

pochodzenie biologiczne

non-animal source

agency

USP/NF
meets EP testing specifications
meets JP testing specifications
meets USP testing specifications

linia produktu

BioXtra

Próba

99.0-101.0%

Formularz

powder

jakość

meets EP, JP, USP testing specifications

metody

cell culture | mammalian: suitable

zanieczyszczenia

endotoxin, tested

kolor

white

mp

284 °C (dec.) (lit.)

rozpuszczalność

H2O: 25 mg/mL

Zastosowanie

peptide synthesis
pharmaceutical (small molecule)

ciąg SMILES

CSCC[C@H](N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

Klucz InChI

FFEARJCKVFRZRR-BYPYZUCNSA-N

informacje o genach

rat ... Ggt1(116568)

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Zastosowanie

L-Methionine has been used as a component of media to culture various cancer cells and to study its effects on the cell cycle.[1] It has also been used as a component of DMEM medium to culture satellite cells from the white muscle of trouts.[2]

Działania biochem./fizjol.

Methionine is an essential amino acid which acts a precursor for transmethylation and transsulphuration. In proteins, L-methionine is the biologically active form.[3] The adenosylation of methionine results in the formation of S-adenosyl-L-methionine (SAM), which serves as a methyl donor to various substances. L-Methionine′s metabolic product glutathione is known to regulate immune response and has antiviral action.[4]
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)

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Certyfikaty analizy (CoA)

Lot/Batch Number
0000432914
0000432913
0000432912
0000432911
0000432911

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L-methionine as immune supportive supplement: a clinical evaluation.
Van Brummelen
Amino Acids, 33(1) (2007)
miR-210 expression is associated with methionine-induced
differentiation of trout satellite cells
Mary Latimer
The Journal of Experimental Biology (2017)
Suppression by L-Methionine of Cell Cycle Progression in LNCaP and MCF-7 Cells but not Benign Cells
Maximo A
Anticancer Research (2010)
Bio-Methionine Production from Glucose - Cost Analysis - Methionine E31A (2016)
Chien-Kuang Cornelia Ding et al.
Nature metabolism, 2(3), 270-277 (2020-05-29)
Critical to the bacterial stringent response is the rapid relocation of resources from proliferation toward stress survival through the respective accumulation and degradation of (p)ppGpp by RelA and SpoT homologues. While mammalian genomes encode MESH1, a homologue of the bacterial
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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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