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I5523

Insulin from porcine pancreas

Name: Insulin from porcine pancreas
Brand: SIGMA
Price: 762 PLN

powder, ≥27 USP units/mg

1 of 2 reviewers received a sample product or took part in a promotion

Synonim(y):

Insulin from hog pancreas

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Do Państwa/SKU	Dostępność	Cena netto
10 mg	Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności	762,00 zł
50 mg	Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności	2680,00 zł

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):

C₂₅₆H₃₈₁N₆₅O₇₆S₆

Numer CAS:

12584-58-6

Masa cząsteczkowa:

5777.54

UNSPSC Code:

12352202

NACRES:

NA.32

EC Number:

235-703-3

MDL number:

MFCD00131380

Biological source:

Porcine pancreas

Form:

powder

Assay:

≥98%

762,00 zł

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Pomoc techniczna

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Właściwości

biological source

Porcine pancreas

Quality Segment

200

sterility

non-sterile

assay

≥98%

form

powder

specific activity

≥27 USP units/mg

technique(s)

cell culture | mammalian: suitable

solubility

0.01 M HCl: 5 mg/mL, clear, colorless

cation traces

Zn: 0.20-0.70%

UniProt accession no.

P01315

shipped in

ambient

storage temp.

−20°C

InChI key

NOESYZHRGYRDHS-ZYCCASTOSA-N

Gene Information

pig ... INS(397415)

Opis

Application

Insulin from porcine pancreas has been used:

for culturing of the primary tumors obtained from mice and porcine preantral follicles
to characterize hormones involved in postnatal chicken preadipocyte differentiation in vitro
to check the reduction ability of the Escherichia coli thiol disulfide exchange proteins (DsbA, DsbC, DsbG) towards insulin

Biochem/physiol Actions

Regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.

Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.

Other Notes

InChI: 1S/C256H381N65O76S6/c1-29-131(23)205(313-193(337)104-258)251(391)317-204(130(21)22)247(387)288-159(75-82-200(347)348)217(357)282-156(71-78-189(262)333)221(361)308-183-116-401-402-117-184-242(382)305-178(111-323)239(379)294-162(88-123(7)8)224(364)295-168(95-140-53-61-146(327)62-54-140)227(367)283-154(69-76-187(260)331)218(358)290-161(87-122(5)6)222(362)285-158(74-81-199(345)346)220(360)302-174(101-190(263)334)234(374)298-170(97-142-57-65-148(329)66-58-142)230(370)309-182(241(381)304-176(255(396)397)103-192(265)336)115-400-399-114-181(213(353)272-107-194(338)278-153(72-79-197(341)342)216(356)281-151(51-42-84-270-256(266)267)211(351)271-108-195(339)279-166(93-138-46-36-32-37-47-138)226(366)297-167(94-139-48-38-33-39-49-139)229(369)299-171(98-143-59-67-149(330)68-60-143)237(377)320-208(136(28)326)253(393)321-85-43-52-186(321)245(385)286-152(50-40-41-83-257)214(354)277-134(26)254(394)395)311-249(389)203(129(19)20)316-235(375)164(90-125(11)12)292-228(368)169(96-141-55-63-147(328)64-56-141)296-223(363)160(86-121(3)4)289-209(349)133(25)276-215(355)157(73-80-198(343)344)287-246(386)202(128(17)18)315-236(376)165(91-126(13)14)293-232(372)173(100-145-106-269-120-275-145)301-238(378)177(110-322)280-196(340)109-273-212(352)180(113-398-403-118-185(310-243(183)383)244(384)319-207(135(27)325)252(392)306-179(112-324)240(380)318-206(132(24)30-2)250(390)312-184)307-225(365)163(89-124(9)10)291-231(371)172(99-144-105-268-119-274-144)300-219(359)155(70-77-188(261)332)284-233(373)175(102-191(264)335)303-248(388)201(127(15)16)314-210(350)150(259)92-137-44-34-31-35-45-137/h31-39,44-49,53-68,105-106,119-136,150-186,201-208,322-330H,29-30,40-43,50-52,69-104,107-118,257-259H2,1-28H3,(H2,260,331)(H2,261,332)(H2,262,333)(H2,263,334)(H2,264,335)(H2,265,336)(H,268,274)(H,269,275)(H,271,351)(H,272,353)(H,273,352)(H,276,355)(H,277,354)(H,278,338)(H,279,339)(H,280,340)(H,281,356)(H,282,357)(H,283,367)(H,284,373)(H,285,362)(H,286,385)(H,287,386)(H,288,387)(H,289,349)(H,290,358)(H,291,371)(H,292,368)(H,293,372)(H,294,379)(H,295,364)(H,296,363)(H,297,366)(H,298,374)(H,299,369)(H,300,359)(H,301,378)(H,302,360)(H,303,388)(H,304,381)(H,305,382)(H,306,392)(H,307,365)(H,308,361)(H,309,370)(H,310,383)(H,311,389)(H,312,390)(H,313,337)(H,314,350)(H,315,376)(H,316,375)(H,317,391)(H,318,380)(H,319,384)(H,320,377)(H,341,342)(H,343,344)(H,345,346)(H,347,348)(H,394,395)(H,396,397)(H4,266,267,270)/t131-,132-,133-,134-,135+,136+,150-,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168-,169-,170-,171-,172-,173-,174-,175-,176-,177-,178-,179-,180-,181-,182-,183-,184-,185-,186-,201-,202-,203-,204-,205-,206-,207-,208-/m0/s1

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Ta pozycja	P3292	I6634	I1882
Sigma-Aldrich I5523 Insulin from porcine pancreas	Sigma-Aldrich P3292 Pancreatin from porcine pancreas	Sigma-Aldrich I6634 Insulin from bovine pancreas	Sigma-Aldrich I1882 Insulin from bovine pancreas
description powder, ≥27 USP units/mg	description powder, suitable for cell culture, 4 × USP specifications	description powder, BioReagent, suitable for cell culture	description γ-irradiated, BioXtra, suitable for cell culture, potency: ≥20 units/mg (USP units), lyophilized powder
biological source Porcine pancreas	biological source Porcine pancreas	biological source bovine	biological source bovine
assay ≥98%	assay -	assay -	assay -
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable, single cell analysis: suitable	technique(s) cell culture \| mammalian: suitable
form powder	form powder	form powder	form lyophilized powder
solubility 0.01 M HCl: 5 mg/mL, clear, colorless	solubility -	solubility acetic acid: 2 mg/mL (pH: 2-3), hydrochloric acid: 2 mg/mL (pH: 2-3)	solubility acetic acid: 2 mg/mL (pH: 2-3), hydrochloric acid: 2 mg/mL (pH: 2-3)

Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certyfikaty analizy (CoA)

Lot/Batch Number

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Average Customer Ratings

Overall, average rating value is 3 of 5.

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Dalia
Dalia
Review 1

Votes 0
Charitable Donation

1 out of 5 stars.

Dalia

4 years ago

Easy Loss of Material due to Container and Loss Mass Sold
The twist off cap retains some of the insulin, both on the sides of the screw top and inside the cap top. This meant that it was very difficult to recover 100% of the mass that we purchased. In a 50mg bottle, we only recovered 37mg. This impeded research capabilities and makes the product more expensive than advertised.

A donation to charity was made for this review

Yes
Helpful?
1. Response from Merck KGaA:
  
  Technical Support
  4 years ago
  
  Thank you for reaching out and sharing your review with us. We are sorry to hear about the difficulty in utilizing the product due to the screw top on the 50mg bottle. Your feedback is extremely valuable and has been handed over to our Product Management team for further review and any necessary updates to our product information. Please visit https://www.sigmaaldrich.com/US/en/support/customer-support to submit a Product Technical Inquiry if you need additional support with your issue.
1 Ratings-only review

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Insulin from porcine pancreas

powder, ≥27 USP units/mg

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Informacje o tej pozycji

I5523-10MG

762,00 zł

biological source

Quality Segment

sterility

assay

form

specific activity

technique(s)

solubility

cation traces

UniProt accession no.

shipped in

storage temp.

InChI key

Gene Information

Application

Biochem/physiol Actions

Other Notes

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Ta pozycja

Informacja o środkach bezpieczeństwa

Klasa składowania

wgk

flash_point_f

flash_point_c

ppe

Dokumentacja

Certyfikaty analizy (CoA)

Masz już ten produkt?

Questions

Reviews

Rating Snapshot

Average Customer Ratings

Active Filters

Easy Loss of Material due to Container and Loss Mass Sold

Response from Merck KGaA:

1 Ratings-only review