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I3901

IL-1α rat

Name: IL-1α rat
Brand: SIGMA
Price: 2230 PLN

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonim(y):

Interleukin-1α, Lymphocyte activating factor, rIL-1α, IL-1α

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Gabaryty przesyłki	SKU	Dostępność	Cena netto
5 μg		Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności	2230,00 zł

Informacje o tej pozycji

UNSPSC Code:

12352202

NACRES:

NA.77

MDL number:

MFCD01635091

Biological source:

rat

Recombinant:

expressed in E. coli

Assay:

≥97% (SDS-PAGE)

Form:

lyophilized powder

Mol wt:

~18 kDa

Impurities:

≤0.1 EU/μg

2230,00 zł

Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności

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Nazwa produktu

Interleukin-1α from rat, IL-1α, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

biological source

rat

Quality Level

100

recombinant

expressed in E. coli

assay

≥97% (SDS-PAGE)

form

lyophilized powder

potency

1-10 pg/mL ED₅₀

quality

endotoxin tested

mol wt

~18 kDa

packaging

pkg of 5 μg

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Cell Culture & Analysis

Cell Culture Supplements & Reagents

Growth Factors and Cytokines

Molecular Biology & Functional Genomics

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Ta pozycja	H6291	I3650	I2778
Sigma-Aldrich I3901 Interleukin-1α from rat	Sigma-Aldrich H6291 Interleukin-1β human	Sigma-Aldrich I3650 Interleukin-4 from rat	Sigma-Aldrich I2778 Interleukin-1α human
biological source rat	biological source human	biological source rat	biological source human
recombinant expressed in E. coli	recombinant expressed in HEK 293 cells	recombinant expressed in E. coli	recombinant expressed in E. coli
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable
assay ≥97% (SDS-PAGE)	assay ≥95% (SDS-PAGE)	assay ≥97% (SDS-PAGE)	assay ≥98% (SDS-PAGE and HPLC)
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
packaging pkg of 5 μg	packaging pkg of 10 μg	packaging pkg of 5 μg	packaging pkg of 2 and 10 μg

Biochem/physiol Actions

Interleukin-1 (IL-1), originally known as Lymphocyte Activating Factor (LA F), activates T cells and lymphocytes, which then proliferate and secrete Interleukin-2 (IL-2). The proliferative activity of human IL-1α is tested in culture using the murine cell line D10S.

Physical form

Lyophilized from 0.2 μm filtered phosphate buffered saline containing 0.25 mg of bovine serum albumin.

Analysis Note

The biological activity of recombinant rat IL-1α was measured by its ability to stimulate cell proliferation using a mouse helper T cell line, D10.G4.1.

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Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certyfikaty analizy (CoA)

Lot/Batch Number

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Photobiomodulation Promotes Repair Following Spinal Cord Injury by Regulating the Transformation of A1/A2 Reactive Astrocytes.

Xuankang Wang et al.

Frontiers in neuroscience, 15, 768262-768262 (2021-11-20)

After spinal cord injury (SCI), reactive astrocytes can be classified into two distinctive phenotypes according to their different functions: neurotoxic (A1) astrocytes and neuroprotective (A2) astrocytes. Our previous studies proved that photobiomodulation (PBM) can promote motor function recovery and improve

Control of Astrocyte Quiescence and Activation in a Synthetic Brain Hydrogel.

Sualyneth Galarza et al.

Advanced healthcare materials, 9(4), e1901419-e1901419 (2020-01-17)

Bioengineers have designed numerous instructive brain extracellular matrix (ECM) environments with tailored and tunable protein compositions and biomechanical properties in vitro to study astrocyte reactivity during trauma and inflammation. However, a major limitation of both protein-based and synthetic model microenvironments

Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats.

Xuankang Wang et al.

Journal of neuroinflammation, 18(1), 256-256 (2021-11-07)

Neurotoxic microglia and astrocytes begin to activate and participate in pathological processes after spinal cord injury (SCI), subsequently causing severe secondary damage and affecting tissue repair. We have previously reported that photobiomodulation (PBM) can promote functional recovery by reducing neuroinflammation

Molecular cloning and expression of rat interleukin-1 alpha cDNA.

T Nishida et al.

Journal of biochemistry, 105(3), 351-357 (1989-03-01)

A cDNA sequence coding for rat interleukin-1 alpha (IL-1 alpha) has been isolated from a cDNA library that was prepared with mRNA derived from LPS-stimulated rat peritoneal macrophages by using human IL-1 alpha cDNA as a probe. The rat cDNA

Melatonin Ameliorates Axonal Hypomyelination of Periventricular White Matter by Transforming A1 to A2 Astrocyte via JAK2/STAT3 Pathway in Septic Neonatal Rats.

Shuqi Jiang et al.

Journal of inflammation research, 14, 5919-5937 (2021-11-23)

Astrocyte A1/A2 phenotypes may play differential role in the pathogenesis of periventricular white matter (PWM) damage in septic postnatal rats. This study aimed to determine whether melatonin (MEL) would improve the axonal hypomyelination through shifting A1 astrocytes towards A2. One-day-old

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Produkty

Interleukin Family (IL)

Interleukins, released from leukocytes, include IL-1β playing crucial roles in inflammation, immune responses, and anti-tumor immunity.

Powiązane treści

Product Information Sheet-I3901

Numer pozycji handlu globalnego

SKU	NUMER GTIN
I3901-5UG	04061833856437

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