I1637

Ipratropium bromide monohydrate

≥98% (TLC), powder

• Synonim(y): Atropine isopropyl bromide
• Wzór empiryczny (zapis Hilla): C₂₀H₃₀BrNO₃ · H₂O
• Numer CAS: 66985-17-9
• Masa cząsteczkowa: 430.38
• NACRES: NA.77
• PubChem Substance ID: 24277843
• UNSPSC Code: 12352200
• EC Number: 244-873-8
• MDL number: MFCD00792907
• Assay: ≥98% (TLC)
• Form: powder

Właściwości

• assay: ≥98% (TLC)
• form: powder
• color: white
• solubility: H₂O: 10 mg/mL
• originator: Boehringer Ingelheim
• SMILES string: O.[Br-].CC(C)[N@+]1(C)[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3
• InChI: 1S/C20H30NO3.BrH.H2O/c1-14(2)21(3)16-9-10-17(21)12-18(11-16)24-20(23)19(13-22)15-7-5-4-6-8-15;;/h4-8,14,16-19,22H,9-13H2,1-3H3;1H;1H2/q+1;;/p-1/t16-,17+,18+,19?,21?;;
• InChI key: KEWHKYJURDBRMN-XSAPEOHZSA-M
• Gene Information: human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

Opis

Application

Ipratropium bromide monohydrate has been used for the inhibition of peripheral muscarinic receptors in rats.

Biochem/physiol Actions

Ipratropium bromide monohydrate is a nonselective muscarinic acetylcholine receptor antagonist and a bronchodilator. In nebulized form, it is used for treating asthma and obstructive pulmonary diseases. It acts as a β₂ adrenoreceptor agonist. Ipratropium bromide monohydrate is an anticholinergic agent and competes with acetylcholine. It promotes bronchodilation by stimulating sympathetic pathways.

Features and Benefits

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Other Notes

N-isopropyl quaternary salt of atropine.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H332,H319
• pcodes: P261 - P264 - P271 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 2