H7660

Heregulin-β1 (EGF Domain) human

≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder

• Synonim(y): HRG-β1
• UNSPSC Code: 12352202
• NACRES: NA.32
• MDL number: MFCD03457066

Właściwości

• biological source: human
• Quality Segment: 200
• recombinant: expressed in E. coli
• assay: ≥98% (SDS-PAGE)
• form: lyophilized powder
• potency: <0.50 ng/mL
• mol wt: predicted mol wt 8 kDa
• packaging: pkg of 10 and 50 μg
• storage condition: avoid repeated freeze/thaw cycles
• impurities: endotoxin, tested
• color: white
• UniProt accession no.: Q02297
• storage temp.: −20°C
• Gene Information: human ... NRG1(3084)

Opis

Biochem/physiol Actions

Growth factor ligand for ErbB3 and ErbB4 receptor tyrosine kinases.

Growth factor ligand for ErbB3 and ErbB4 receptor tyrosine kinases. The binding of HRG results in receptor dimerization and receptor trans-autophosphorylation. The phosphorylated receptors recruit cellular signaling proteins, initiating signaling pathways.

Analysis Note

The biological activity is measured by its ability to stimulate the proliferation of human MCF-7 cells grown under serum-free conditions.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)