F8307

FR-900098 monosodium salt

≥97% (NMR)

• Synonim(y): (3-(Acetylhydroxyamino)propyl)-phosphonic acid, BRN 2096083, P-[3-(Acetylhydroxyamino)propyl]-phosphonic acid
• Wzór empiryczny (zapis Hilla): C₅H₁₁NNaO₅P
• Numer CAS: 73226-73-0
• Masa cząsteczkowa: 219.11
• NACRES: NA.77
• PubChem Substance ID: 329799770
• UNSPSC Code: 51111800
• MDL number: MFCD17215926
• Assay: ≥97% (NMR)
• Form: powder
• Storage condition: desiccated, protect from light

Właściwości

• assay: ≥97% (NMR)
• form: powder
• storage condition: desiccated, protect from light
• color: white to light brown
• solubility: H₂O: ≥20 mg/mL
• storage temp.: −20°C
• SMILES string: [Na+].CC(=O)N(O)CCCP(O)([O-])=O
• InChI: 1S/C5H12NO5P.Na/c1-5(7)6(8)3-2-4-12(9,10)11;/h8H,2-4H2,1H3,(H2,9,10,11);/q;+1/p-1
• InChI key: LCFXFDGYDKNWMD-UHFFFAOYSA-M

Opis

Biochem/physiol Actions

1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative, Gram-positive bacteria, plants, and the parasite causing the most virulent form of malaria, Plasmodium falciparum (Mammals produce isoprenoids via the mevalonate pathway). Inhibiton of the enzyme provides alternative to traditional antimalaria therapy. FR-900098 is twice more effective than fosmidomycin against various strains of P. falciparum in vitro and the closely related P. vinckei in mice.

1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable