D3689

(S)-3,5-Dihydroxyphenylglycine hydrate

≥98% (HPLC), group I metabotropic glutamate receptor agonist, powder

• Synonim(y): S-DHPG
• Wzór empiryczny (zapis Hilla): C₈H₉NO₄ · xH₂O
• Numer CAS: 162870-29-3
• Masa cząsteczkowa: 183.16 (anhydrous basis)
• UNSPSC Code: 12352209
• PubChem Substance ID: 24278366
• NACRES: NA.77
• MDL number: MFCD11044457
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated, protect from light

Właściwości

• Nazwa produktu: (S)-3,5-Dihydroxyphenylglycine hydrate, ≥98% (HPLC), powder
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated, protect from light
• color: white
• storage temp.: −20°C
• SMILES string: O.N[C@H](C(O)=O)c1cc(O)cc(O)c1
• InChI: 1S/C8H9NO4.H2O/c9-7(8(12)13)4-1-5(10)3-6(11)2-4;/h1-3,7,10-11H,9H2,(H,12,13);1H2/t7-;/m0./s1
• InChI key: QZEFIWWBQUKNFA-FJXQXJEOSA-N
• Gene Information: human ... GRM1(2911)

Opis

Application

(S)-3,5-Dihydroxyphenylglycine hydrate has been used:

• as mGluR1/5 agonist for metabotropic glutamate receptor 1 (mGluR1/5) activation in synaptoneurosomal preparations
• in ACSF for DHPG stimulation
• to inject into basolateral amygdala to study its effect on memory expression

Biochem/physiol Actions

(S)-3,5-Dihydroxyphenylglycine hydrate is a group I metabotropic glutamate receptor agonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Disclaimer

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves