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C6348
Monoclonal Anti-CXCR2 (IL-8 RB) antibody produced in mouse
clone 48311, purified immunoglobulin, lyophilized powder
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| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
|---|---|---|---|
| 0.5 mg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 3180,00 zł |
Informacje o tej pozycji
Conjugate:
unconjugated
Clone:
48311, monoclonal
Application:
FACS, Neutral
Citations:
3
3180,00 zł
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
Rekombinowane, niezawierające konserwantów przeciwciało jest dostępne dla Twojego celu. Wypróbuj ZRB2964
Pomoc techniczna
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Pozwól nam pomócbiological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
48311, monoclonal
form
lyophilized powder
species reactivity
human
technique(s)
flow cytometry: suitable, neutralization: suitable
isotype
IgG2a
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... IL8RB(3579)
mouse ... Il8rb(12765)
General description
The antibody will neutralize human cell surface CXCR-2 mediated-myloperoxidase release from human granulocytes induced by GROα. It will not block myeloperoxidase release induced by IL-8. The antibody reacts with human CXCR-2 transfectant cells and not the parent cell line. The antibody shows no cross-reactivity with CXCR-1.
Immunogen
human CXCR2 transfected NSO mouse myeloma cells.
Biochem/physiol Actions
CXCR2 is a G protein-coupled receptor that binds IL-8 with high affinity. It mediates migration of neutrophils to the sites of inflammation. It also binds CXCL1 and stimulates growth of melanomas.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.
Preparation Note
Purified using protein G.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Ta pozycja | |||
|---|---|---|---|
| biological source mouse | biological source mouse | biological source rat | biological source rabbit |
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| antibody form purified immunoglobulin | antibody form purified immunoglobulin | antibody form purified antibody | antibody form IgG fraction of antiserum |
| species reactivity human | species reactivity human | species reactivity mouse | species reactivity human |
| Gene Information human ... IL8RB(3579) | Gene Information human ... IL8RA(3577) | Gene Information mouse ... Il2Rb(16185) | Gene Information human ... CXCR4(7852) |
| clone 48311, monoclonal | clone 42705.111, monoclonal | clone TM-beta 1, monoclonal | clone polyclonal |
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Klasa składowania
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Powiązane treści
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Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| C6348-.5MG | 04061832714035 |