A6608

Albumin human

recombinant, expressed in Saccharomyces cerevisiae, aqueous solution, 10% in aqueous buffer, ≥99% (agarose gel electrophoresis)

• Synonim(y): rHSA
• Wzór empiryczny (zapis Hilla): C₂₉₃₆H₄₆₂₄N₇₈₆O₈₈₉S₄₁
• Numer CAS: 70024-90-7
• Masa cząsteczkowa: 66471.53
• UNSPSC Code: 12352202
• eCl@ss: 42010201
• NACRES: NA.25
• MDL number: MFCD00081418
• Biological source: human
• Assay: ≥99% (agarose gel electrophoresis)
• Form: aqueous solution
• Technique(s): cell culture | mammalian: suitable
• Concentration: 10% in aqueous buffer

Właściwości

• biological source: human
• Quality Segment: 200
• recombinant: expressed in Saccharomyces cerevisiae
• assay: ≥99% (agarose gel electrophoresis)
• form: aqueous solution
• mol wt: monomer ~67 kDa
• concentration: 10% in aqueous buffer
• technique(s): cell culture | mammalian: suitable
• UniProt accession no.: P02768
• storage temp.: 2-8°C
• SMILES string: FC(F)(F)C(F)(F)C(F)(F)F
• InChI: 1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
• InChI key: QYSGYZVSCZSLHT-UHFFFAOYSA-N
• Gene Information: human ... ALB(213)

Opis

General description

Albumin constitutes 25% of the proteins produced by the liver and is a prominent protein found in the blood. It is a protein of a single polypeptide chain with a thiol group.

Application

Albumin human has been used:

• to study its adsorption process on model mica surface at pH 3.5 using the atomic force microscopy (AFM) and in situ streaming potential measurements[1]
• to study its proteolytic activities under reducing conditions[2]
• in the medium for stem cell cultivation[3]

This recombinant variant is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells.

Biochem/physiol Actions

Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.

Albumin is a binding and transport protein that serves as a protein repository and a carrier for amino acids. Albumin binding dissolves the biomolecules in blood and ensures its effective transport. This also prevents the loss of substance through excretion. Pathological conditions like vasculitis, lymphangiectasia, glomerulonephritis, and hepatic sinusoidal hypertension might result in hypoalbuminemia. This product can be used in the pharmaceutical industry as a drug excipient and to coat medical devices.[1]

Analysis Note

Endotoxin tested

Other Notes

View more information on human serum albumin.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 10 - Combustible liquids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable