This product is intended for research use only and not suitable for human or veterinary use. This material is not tested for in vivo or in vitro applications. However, there are available publications referencing this compound being used successfully in animal models. Please see the link below to review an example of one such paper:
https://www.sciencedirect.com/science/article/pii/S2211124719300671?via%3Dihub
Przejdź do
A5602
AMD3100 octahydrochloride hydrate
≥97% (NMR), solid, CXCR4 antagonist
Synonim(y):
1,1′-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane octahydrochloride, JM3100, Plerixafor, SID791
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| Do Państwa/SKU | Dostępność | Cena netto |
|---|---|---|
5 mg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 955,00 zł |
Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C28H54N8 · 8HCl · xH2O
Numer CAS:
Masa cząsteczkowa:
794.47 (anhydrous basis)
MDL number:
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
Assay:
≥97% (NMR)
Form:
solid
Storage condition:
desiccated
955,00 zł
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
Pomoc techniczna
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Pozwól nam pomócNazwa produktu
AMD3100 octahydrochloride hydrate, ≥97% (NMR), solid
Quality Segment
assay
≥97% (NMR)
form
solid
storage condition
desiccated
solubility
H2O: ≥10 mg/mL, clear
originator
Sanofi Aventis
storage temp.
−20°C
SMILES string
Cl[H].Cl[H].Cl[H].Cl[H].Cl[H].Cl[H].Cl[H].Cl[H].[H]O[H].C1CNCCNCCCN(CCNC1)Cc2ccc(CN3CCCNCCNCCCNCC3)cc2
InChI
1S/C28H54N8.8ClH.H2O/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36;;;;;;;;;/h5-8,29-34H,1-4,9-26H2;8*1H;1H2
InChI key
GKFHDCZYJHUPEN-UHFFFAOYSA-N
Application
AMD3100 is a highly specific chemokine receptor CXCR4 antagonist. AMD3100 has been used in a study to determine the blockade of CXCR4 in oral squamous cell carcinoma and inhibition of lymph node metastases.
Biochem/physiol Actions
AMD3100 is a highly specific chemokine receptor CXCR4 antagonist.
Features and Benefits
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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Ta pozycja | |||
|---|---|---|---|
| assay ≥97% (NMR) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form solid | form solid | form solid | form liquid |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −70°C |
| solubility H2O: ≥10 mg/mL, clear | solubility water: 10 mg/mL | solubility DMSO: >10 mg/mL, H2O: insoluble | solubility - |
| storage condition desiccated | storage condition OK to freeze, desiccated (hygroscopic), protect from light | storage condition - | storage condition OK to freeze, avoid repeated freeze/thaw cycles, protect from light |
Klasa składowania
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
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is this pharmaceutical grade for use in vivo? cat A5602-5mg AMD3100
1 answer-
Helpful?
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What is the solubility of Product A5602, AMD3100 octahydrochloride hydrate?
1 answer-
AMD3100 octahydrochloride hydrate is soluble in water at 22 mg/ml.
Helpful?
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Can solutions of Product A5602, AMD3100 octahydrochloride hydrate, be stored?
1 answer-
Sigma-Aldrich has not evaluated the solution stability of A5602. If no information on the solution stability is found from a literature search, we would recommend that that you prepare solutions fresh.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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What biological effects has been reported for Product A5602, AMD3100 octahydrochloride hydrate?
1 answer-
This is a highly specific chemokine receptor CXCR4 antagonist. CXCR4 has been implicated in inflammation, cancer, and HIV infection.
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