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A3785

5-Aminolevulinic acid hydrochloride

≥98%, suitable for ligand binding assays

Synonim(y):

δ-Aminolevulinic acid hydrochloride, 5-Amino-4-oxopentanoic acid hydrochloride, 5-Aminolaevulinic acid hydrochloride, ALA

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Do Państwa/SKUDostępnośćCena netto
500 mg
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
1000,00 zł
1 g
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
1810,00 zł
5 g
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6910,00 zł

Informacje o tej pozycji

Wzór liniowy:
NH2CH2C(O)CH2CH2COOH · HCl
Numer CAS:
Masa cząsteczkowa:
167.59
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
226-679-5
MDL number:
Beilstein/REAXYS Number:
3690651

1000,00 zł


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Nazwa produktu

5-Aminolevulinic acid hydrochloride, ≥98%

Quality Segment

assay

≥98%

form

powder

technique(s)

ligand binding assay: suitable

mp

150 °C

storage temp.

−20°C

SMILES string

Cl[H].NCC(=O)CCC(O)=O

InChI

1S/C5H9NO3.ClH/c6-3-4(7)1-2-5(8)9;/h1-3,6H2,(H,8,9);1H

InChI key

ZLHFONARZHCSET-UHFFFAOYSA-N

Application

5-Aminolevulinic acid hydrochloride has been used to activate or inhibit heme biosynthesis in HeLa and K562 cell lines.[1] It has also been used in photodynamic therapy for A431 tumor bearing mice.

Biochem/physiol Actions

Intermediate in heme biosynthesis.
5-Aminolevulinic acid (5-ALA) is an intermediate in heme biosynthesis and is useful in cancer treatment. It is a non-protein amino acid. 5-ALA also has applications in the field of agriculture. It is being studied as an inducing reagent for protoporphyrin IX (PPIX) dependent fluorescence diagnosis of metastatic lymph nodes. 5-ALA is used for photodynamic therapy of diseases, such as Paget′s disease and HPV infection-associated cervical condylomata acuminata.
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Ta pozycja
A7793T4626A5575
form

powder

form

powder

form

powder

form

powder

technique(s)

ligand binding assay: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

ligand binding assay: suitable

technique(s)

-

assay

≥98%

assay

≥98%

assay

≥98% (TLC)

assay

≥98% (TLC)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

200

mp

150 °C

mp

-

mp

145-147 (lit.)

mp

-


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Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Certyfikaty analizy (CoA)

Lot/Batch Number

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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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