As the product name says, the Alternariol is extracted from the species Alternaria sp.
This should be stated in the certificate of origin (CoO). A sample COfO can be pulled from our website;
https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COO/Q12/A1312-5MG037M4176V.pdf
A1312
Alternariol
from Alternaria sp., ~96%, Mycotoxin, powder
Synonim(y):
3,7,9-Trihydroxy-1-methyl-6H-dibenzo[b,d]pyran-6-one
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Wybierz wielkość
5 MG
4030,00 zł
4030,00 zł
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Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C14H10O5
Numer CAS:
Masa cząsteczkowa:
258.23
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
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Pozwól nam pomócNazwa produktu
Alternariol from Alternaria sp., ~96%
assay
~96%
Quality Level
form
powder
storage temp.
2-8°C
SMILES string
Cc1cc(O)cc2OC(=O)c3c(O)cc(O)cc3-c12
InChI
1S/C14H10O5/c1-6-2-7(15)5-11-12(6)9-3-8(16)4-10(17)13(9)14(18)19-11/h2-5,15-17H,1H3
InChI key
CEBXXEKPIIDJHL-UHFFFAOYSA-N
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Ta pozycja | |||
|---|---|---|---|
| assay ~96% | assay - | assay - | assay - |
| form powder | form - | form powder | form powder |
| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level 300 |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
General description
Alternariol belongs to the dibenzo-pyrones chemical group. It is a mycotoxin present in indoor air, soil and plants.
Application
Alternariol from Alternaria sp. may be used as a calibration standard in reverse phase high-performance liquid chromatography (HPLC) and UV-spectrum analysis. It may also be used to spike wholemeal wheat flour for wet baking studies [1]
Biochem/physiol Actions
Alternaria mycotoxins are generally associated with undried food grains post-harvest. The disease caused by Alternaria mycotoxin results in a discolored halo in fruits and spotting in leaves. Alternariol (AOH) is cytotoxic and fetotoxic to microbes and mammalian cells. AOH displays inhibitory effect on cell proliferation and has estrogenic functionality.
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
Klasa składowania
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Alternaria mycotoxins in food and feed: an overview
EscrivaL, et al.
Journal of Food Quality, 2017 (2017)
David Siegel et al.
Journal of agricultural and food chemistry, 58(17), 9622-9630 (2010-08-07)
The stability of the Alternaria mycotoxins alternariol, alternariol monomethyl ether, and altenuene upon bread baking was investigated by model experiments using a spiked wholemeal wheat flour matrix. For alternariol and alternariol monomethyl ether, but not for altenuene, degradation products, formed
Detection of alternariol in Estonian grain samples
Kutt ML, et al.
Agronomy Research , 8(Special II), 317-322 (2010)
A Solhaug et al.
Toxicology letters, 219(1), 8-17 (2013-03-05)
The mycotoxin alternariol (AOH), a frequent contaminant in fruit and cereal products, is known to induce DNA damage with subsequent cell cycle arrest. Here we elucidated the effects of AOH on stages of cell cycle progression using the RAW 264.7
Stefanie C Fleck et al.
Toxicology letters, 214(1), 27-32 (2012-08-21)
Altertoxin II (ATX II) is one of the several mycotoxins produced by Alternaria fungi. It has a perylene quinone structure and is highly mutagenic in Ames Salmonella typhimurium, but its mutagenicity in mammalian cells has not been studied before. Here
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| A1312-5MG | 04061832938394 |
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I am currently using your product "Alternariol from Alternaria sp. (~96%)", Product Number A1312, for my research. I would like to ask which specific Alternaria species was used as the source for this compound.
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