427M-9

p27^Kip1 (SX53G8) Mouse Monoclonal Antibody

• NACRES: NA.41
• UNSPSC Code: 12352203
• Conjugate: unconjugated
• Clone: SX53G8, monoclonal
• Application: IHC (p)
• Citations: 11

Właściwości

• biological source: mouse
• Quality Segment: 100, 500
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: SX53G8, monoclonal
• description: For In Vitro Diagnostic Use in Select Regions (See Chart)
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (427M-94), vial of 0.5 mL concentrate (427M-95), bottle of 1.0 mL predilute (427M-97), vial of 1.0 mL concentrate (427M-96), bottle of 7.0 mL predilute (427M-98)
• manufacturer/tradename: Cell Marque^®
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
• isotype: IgG1κ
• control: tonsil
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: nuclear
• Gene Information: rat ... Cdkn1B(83571)

Opis

General description

p27 is a cyclin-dependent kinase inhibitor which regulates progression from G1 to S phase by binding and inhibiting cyclin-dependent kinases. Low p27 expression has been associated with unfavorable prognosis in renal cell carcinoma, colon carcinoma, small breast carcinomas, non-small-cell lung carcinoma, hepatocellular carcinoma, multiple myeloma, lymph node metastases in Papillary carcinoma of the Thyroid, and more aggressive phenotype in carcinoma of the cervix.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note

IVD

IVD

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: [email protected]

p27Kip1 Positive Control Slides, Product No. 427S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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