The target information for UniProt accession P23771 indicates that it is a transcriptional activator that binds to the enhancer of the T-cell receptor alpha and delta genes. It specifically binds to the consensus sequence 5'-AGATAG-3'.
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390M-1
GATA3 (L50-823) Mouse Monoclonal Antibody
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Informacje o tej pozycji
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
L50-823, monoclonal
Application:
IHC (p)
Citations:
5
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Pozwól nam pomócbiological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
L50-823, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (390M-14), vial of 0.5 mL concentrate (390M-15), bottle of 1.0 mL predilute (390M-17), vial of 1.0 mL concentrate (390M-16), bottle of 7.0 mL predilute (390M-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
isotype
IgG1κ
control
breast carcinoma, urothelial carcinoma
shipped in
wet ice
storage temp.
2-8°C
visualization
nuclear
Gene Information
human ... GATA3(2625)
General description
GATA binding protein 3 or GATA3, is a zinc finger transcription factor and plays an important role in promoting and directing cell proliferation, development, and differentiation in many tissues and cell types. The human GATA3 gene has been mapped to chromosome10p15. GATA3 expression is primarily seen in breast carcinoma and urothelial carcinoma. Anti-GATA3 can also be useful in the identification of unknown primary carcinoma when carcinomas of the breast or bladder are a possibility
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Analysis Note
 IVD |  IVD |  IVD |  RUO |
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
GATA3 Positive Control Slides, Product No. 390S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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Do you have any data available on the specific cellular element that is the target for clone L50-823, GATA-3?
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