27885

Coumestrol

≥95.0% (HPLC)

• Synonim(y): 7,12-Dihydroxycoumestan
• Wzór empiryczny (zapis Hilla): C₁₅H₈O₅
• Numer CAS: 479-13-0
• Masa cząsteczkowa: 268.22
• UNSPSC Code: 41116107
• NACRES: NA.77
• PubChem Substance ID: 57648279
• EC Number: 207-525-6
• Beilstein/REAXYS Number: 266702
• MDL number: MFCD00016885
• Assay: ≥95.0% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥95.0% (HPLC)
• form: powder
• impurities: ≤10.0% water
• mp: ≥350 °C (lit.)
• SMILES string: Oc1ccc-2c(OC(=O)c3c-2oc4cc(O)ccc34)c1
• InChI: 1S/C15H8O5/c16-7-1-3-9-11(5-7)19-14-10-4-2-8(17)6-12(10)20-15(18)13(9)14/h1-6,16-17H
• InChI key: ZZIALNLLNHEQPJ-UHFFFAOYSA-N
• Gene Information: human ... ESR1(2099), ESR2(2100) ; mouse ... Esr1(13982) ; rat ... Ar(24208)

Opis

Application

• Phytoestrogens in Fish Feed Production:Coumestrolis is used as a biomarkers in fish feed production, facilitating the assessment of plant raw materials used in these feeds (Pavlopoulos et al., 2023).


• Coumestrol and Soybean Leaf Senescence: Coumestrol′s role in soybean leaf senescence is explored, particularly its interactions with phytohormones, suggesting potential agronomic benefits and applications in crop science, it acts as a phytoalexin (Mun et al., 2021).


• Systemic Defense in Soybeans: Investigating the effects of priming with coumestrol on soybean defense against the root-lesion nematode, this research highlights its potential as a natural plant defense enhancer (Adss et al., 2021).

Biochem/physiol Actions

Coumestrol has anti-estrogenic actions in the brain and pituitary, mediated through estrogen receptor-α.[1]

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves