232R-1

Calretinin (SP13) Rabbit Monoclonal Antibody

• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100; 500
• białko sprzężone: unconjugated
• forma przeciwciała: culture supernatant
• rodzaj przeciwciała: primary antibodies
• klon: SP13, monoclonal
• opis: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Formularz: buffered aqueous solution
• reaktywność gatunkowa: human
• opakowanie: vial of 0.1 mL concentrate (232R-14); vial of 0.5 mL concentrate (232R-15); bottle of 1.0 mL predilute (232R-17); vial of 1.0 mL concentrate (232R-16); bottle of 7.0 mL predilute (232R-18)
• producent / nazwa handlowa: Cell Marque^®
• metody: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
• izotyp: IgG1
• kontrola: mesothelioma
• Warunki transportu: wet ice
• temp. przechowywania: 2-8°C
• wizualizacja: cytoplasmic, nuclear

Opis

Opis ogólny

Calretinin is a 29 kDa calcium-binding protein thought to play a role in the cell cycle. Anti-calretinin has been shown to be useful in differentiating mesothelioma from adenocarcinomas from the lung and other sources.[1] The sensitivity of anti-calretinin in distinguishing reactive mesothelial cells from adenocarcinoma cells is 100%, and the specificity is up to 80%. Light, focal, cytoplasmic staining of adenocarcinoma cells may be seen in 10 to 30% of cases.[2] Anti-calretinin has also demonstrated utility in differentiating adrenal cortical neoplasms (+) from pheochromocytomas (-).[3][4] Calretinin has also been useful in diagnosing granulosa cell tumor of the ovary amongst its mimics. Other ovarian tumors that stain with calretinin are Sertoli-Leydig cell tumor, Sertoli cell tumor, Leydig cell tumor, and sex cord tumor with annular tubules, as well as steroid cell tumor.[5][6][7][8]⁹

Powiązanie

Calretinin Positive Control Slides, Product No. 232S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Postać fizyczna

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Uwaga dotycząca przygotowania

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Inne uwagi

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Informacje prawne

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable