N-Hexanoyl-DL-homoserine lactone

Name: N-Hexanoyl-<SC>DL</SC>-homoserine lactone
Brand: SIGMA
Price: 1120 PLN

≥97.0% (HPLC)

Synonim(y):

N-Caproyl-DL-homoserine lactone

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25 MG

1120,00 zł

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Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):

C₁₀H₁₇NO₃

Numer CAS:

106983-28-2

Masa cząsteczkowa:

199.25

UNSPSC Code:

12352209

eCl@ss:

32160406

PubChem Substance ID:

329748862

NACRES:

NA.26

Beilstein/REAXYS Number:

1640340

MDL number:

MFCD01862908

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InChI key

ZJFKKPDLNLCPNP-UHFFFAOYSA-N

InChI

1S/C10H17NO3/c1-2-3-4-5-9(12)11-8-6-7-14-10(8)13/h8H,2-7H2,1H3,(H,11,12)

assay

≥97.0% (HPLC)

form

powder or crystals

technique(s)

LC/MS: suitable

color

white to faint beige

mp

101-106 °C

storage temp.

2-8°C

Quality Level

100

Powiązane kategorie

Biochemicals

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Ta pozycja	56395	10937	10940
Sigma-Aldrich 09926 N-Hexanoyl-DL-homoserine lactone	Sigma-Aldrich 56395 N-Hexanoyl-L-homoserine lactone	Sigma-Aldrich 10937 N-Tetradecanoyl-DL-homoserine lactone	Sigma-Aldrich 10940 N-Octanoyl-DL-homoserine lactone
form powder or crystals	form powder or crystals	form powder	form powder with small lumps
assay ≥97.0% (HPLC)	assay ≥96% (HPLC)	assay ≥97.0% (HPLC)	assay ≥97.0% (HPLC)
technique(s) LC/MS: suitable	technique(s) -	technique(s) -	technique(s) -
storage temp. 2-8°C	storage temp. −20°C	storage temp. 2-8°C	storage temp. 2-8°C
mp 101-106 °C	mp -	mp -	mp -
color white to faint beige	color white to off-white	color white to slightly yellow	color white to faintly beige

Application

Induces violacein expression in a Chromobacterium violaceum mutant usually not able to produce homoserine lactones.[1]

Biochem/physiol Actions

N-Hexanoyl-DL-homoserine lactone is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella and are involved in quorum sensing, cell to cell communication among bacteria. Some AHLs are potent chemoattractants for human immune cells such as neutrophils.

Quorum-sensing signal generation

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Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certyfikaty analizy (CoA)

Lot/Batch Number

BCBT2786

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Odwiedź Bibliotekę dokumentów

Quorum Sensing versus Quenching Bacterial Isolates Obtained from MBR Plants Treating Leachates from Municipal Solid Waste.

Albert Soler et al.

International journal of environmental research and public health, 15(5) (2018-05-23)

Quorum sensing (QS) is a mechanism dependent on bacterial density. This coordinated process is mediated by the synthesis and the secretion of signal molecules, called autoinducers (AIs). N-acyl-homoserine lactones (AHLs) are the most common AIs that are used by Gram-negative

Detection of bacterial contamination in food matrices by integration of quorum sensing in a paper-strip test.

Daniel Wynn et al.

The Analyst, 143(19), 4774-4782 (2018-09-15)

There are an estimated 48 million cases of foodborne illness in the United States every year. In general, these illnesses are the result of unintentional contamination and improper food handling. Because bacterial contamination plays a major role in food spoilage

Manipulation of quorum sensing regulation in Pseudomonas fluorescens NCIMB 10586 to increase mupirocin production.

Joanne Hothersall et al.

Applied microbiology and biotechnology, 90(3), 1017-1026 (2011-02-15)

Transcription of the 74 kb Pseudomonas fluorescens mupirocin [pseudomonic acid (PA)] biosynthesis cluster depends on quorum sensing-dependent regulation via the LuxI/LuxR homologues MupI/MupR. To facilitate analysis of novel PAs from pathway mutants, we investigated factors that affect mup gene expression.

N-acyl homoserinelactone-mediated gene regulation in gram-negative bacteria.

L Eberl

Systematic and applied microbiology, 22(4), 493-506 (2000-05-04)

The view of bacteria as unicellular organisms has strong roots in the tradition of culturing bacteria in liquid media. However, in nature microbial activity is mainly associated with surfaces where bacteria form highly structured and cooperative consortia which are commonly

Quenching of acyl-homoserine lactone-dependent quorum sensing by enzymatic disruption of signal molecules.

Robert Czajkowski et al.

Acta biochimica Polonica, 56(1), 1-16 (2009-03-17)

Many Gram-positive and Gram-negative bacteria communicate using small diffusible signal molecules called autoinducers. This process, known as quorum sensing (QS), links cell density to the expression of genes as diverse as those associated with virulence factors production of plant and

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N-Hexanoyl-DL-homoserine lactone