PHL80229

Madecassic acid

phyproof^® Reference Substance

• Synonim(y): 6β-Hydroxyasiatic acid, Brahmic acid
• Wzór empiryczny (zapis Hilla): C₃₀H₄₈O₆
• Numer CAS: 18449-41-7
• Masa cząsteczkowa: 504.70
• Kod UNSPSC: 41116107
• NACRES: NA.24

Właściwości

• klasa czystości: primary reference standard
• linia produktu: phyproof^® Reference Substance
• Próba: ≥90.0% (HPLC)
• producent / nazwa handlowa: PhytoLab
• Zastosowanie: food and beverages
• format: neat
• InChI: 1S/C30H48O6/c1-16-9-10-30(25(35)36)12-11-28(5)18(22(30)17(16)2)7-8-21-26(3)13-20(33)24(34)27(4,15-31)23(26)19(32)14-29(21,28)6/h7,16-17,19-24,31-34H,8-15H2,1-6H3,(H,35,36)/t16-,17+,19-,20-,21-,22+,23-,24+,26-,27+,28-,29-,30+/m1/s1
• Klucz InChI: PRAUVHZJPXOEIF-AOLYGAPISA-N

Opis

Opis ogólny

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Zastosowanie

• Antidepressant potential of triterpenoids: Madecassic acid, identified as a key triterpenoid in Centella asiatica, is explored for its antidepressant properties through in vivo and computational studies, underscoring its potential role in neuropsychiatric disorder treatments (Mando et al., 2024).


• Cardiotoxicity assessment: Research indicates that madecassic acid can induce cardiotoxicity by promoting inflammation and generating excessive reactive oxygen species, highlighting critical safety concerns in its pharmacological use (Guo et al., 2024).


• Neuroprotective effects in cognitive decline: A study demonstrates that Centella asiatica, containing madecassic acid, enhances memory and executive functions in aging rats, suggesting its therapeutic efficacy against age-related cognitive disorders (Firdaus et al., 2024).


• Anti-angiogenic properties: Madecassic acid is investigated for its role in inhibiting angiogenesis, with network pharmacology and experimental validation pointing to potential applications in cancer treatment strategies (Zhao et al., 2024).


• Antioxidative and anti-inflammatory effects: This compound from Centella asiatica extract is shown to exert antioxidative and anti-neuroinflammatory effects, particularly beneficial in neurodegenerative diseases like Alzheimer′s (Hambali et al., 2024).

Informacje prawne

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable