Unless otherwise stated, this product is intended for research use only. It is not suitable for any other purpose, which includes, but is not limited to, unauthorized commercial use, in vitro diagnostic use, or therapeutic use in humans or animals.
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G6257
Glutaraldehyde solution
Grade II, 25% in H2O
Synonim(y):
Glutaric dialdehyde solution, Pentane-1,5-dial
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| Do Państwa/SKU | Dostępność | Cena netto |
|---|---|---|
10 mL | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 91,50 zł |
100 mL | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 285,00 zł |
10 x 10 mL | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 390,00 zł |
1 L | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 807,00 zł |
Informacje o tej pozycji
Wzór liniowy:
OHC(CH2)3CHO
Numer CAS:
Masa cząsteczkowa:
100.12
UNSPSC Code:
12352114
NACRES:
NA.21
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
605390
Form:
liquid
91,50 zł
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
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Pozwól nam pomóctype
Grade II
Quality Segment
form
liquid
concentration
25% in H2O
technique(s)
electron microscopy: suitable
color
colorless
useful pH range
2.9
mp
-10 °C ((14 °F ))
solubility
water: soluble
application(s)
cell analysis
sample preparation
SMILES string
[H]C(CCCC([H])=O)=O
InChI
1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2
InChI key
SXRSQZLOMIGNAQ-UHFFFAOYSA-N
General description
Glutaraldehyde, known as Glutaric dialdehyde or Pentane-1,5-dial, serves as a versatile reagent with applications spanning various research domains, including cell biology and biochemical research. It finds applications as a protein crosslinker, aids in enzyme immobilization for microscopy, and contributes to histochemistry and cytochemistry processes. As an amine-reactive homobifunctional crosslinker, it acts as a cell fixative before procedures like SDS-PAGE, staining, or electron microscopy, making it a valuable tool for diverse morphological studies.
Glutaraldehyde demonstrates efficacy in crosslinking amine and hydrazine derivatives to proteins and other amine-containing polymers. Notably, it allows direct coupling of biotin hydrazides to nucleic acids, offering potential applications in conjugating fluorescent hydrazides and hydroxylamines to DNA. Moreover, in histology studies, Glutaraldehyde is employed for preserving tissue sections and preparing them for detailed examination.
Glutaraldehyde demonstrates efficacy in crosslinking amine and hydrazine derivatives to proteins and other amine-containing polymers. Notably, it allows direct coupling of biotin hydrazides to nucleic acids, offering potential applications in conjugating fluorescent hydrazides and hydroxylamines to DNA. Moreover, in histology studies, Glutaraldehyde is employed for preserving tissue sections and preparing them for detailed examination.
Application
Glutaraldehyde solution has been used:
- for fixation of mouse and esophageal cancer cell lines
- to crosslink amyloid-β protein
- to crosslink gelatin in 3D scaffold preparation of trachea
Biochem/physiol Actions
Glutaraldehyde is an effective protein crosslinker and finds application in techniques like enzyme immobilisation microscopy, histochemistry and cytochemistry. It exists in different forms under acidic or neutral conditions. It is toxic to aquatic organisms. Its allergic nature leads to hypersensitivity reactions. Contact of glutaraldehyde vapors in endoscopy contributes to Colitis.
Features and Benefits
- Versatile and adaptable for wide variety of research applications
- Ready-made solution reduces the need for preparation time
Packaging
Not refrigerated en route
Preparation Note
Not specially purified.
Other Notes
For additional information on our range of Biochemicals, please complete this form.
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Disclaimer
“The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.”
This grade is not recommended for use as an electron microscopy fixative.
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Ta pozycja | |||
|---|---|---|---|
| Quality Level 200 | Quality Level 200 | Quality Level 300 | Quality Level 300 |
| solubility water: soluble | solubility water: soluble | solubility water: soluble at 20 °C | solubility water: soluble |
| form liquid | form liquid | form liquid | form liquid |
| mp -10 °C ((14 °F )) | mp -21 °C ((-6 °F)) | mp -10 °C ((14 °F )) | mp -21 °C ((-6 °F)) |
| concentration 25% in H2O | concentration 50 wt. % in H2O | concentration 25% in H2O | concentration 50% in H2O |
| color colorless | color colorless | color colorless | color colorless |
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Danger
Hazard Classifications
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
supp_hazards
Klasa składowania
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Wykazy regulacyjne
Wykazy regulacyjne dotyczą głównie produktów chemicznych. Można w nich podawać ograniczoną liczbę informacji na temat produktów niechemicznych. Brak wpisu oznacza, że żaden ze składników nie znajduje się w wykazie. Użytkownik odpowiada za zagwarantowanie bezpiecznego i zgodnego z prawem stosowania produktu.
111-30-8
CAS No.
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Is this product surgery grade? Can it be used to fixate pericardium for implantation in humans?
1 answer-
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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Is the 25% concentration in terms of w/w or w/v?
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This product is a 25% weight per weight (w/w) solution.
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What type of product should be ordered to ensure that each lot provides clear glutaraldehyde solutions?
1 answer-
Grade II glutaraldehyde solutions may exhibit variation in color between lots. For consistent clarity, it is advisable to order Grade I glutaraldehyde, which is a purer product. This higher-grade variant must be stored frozen and is shipped with wet or dry ice. While Grade II is often suitable for industrial or technical applications, Grade I glutaraldehyde solutions are designed for more precise applications, such as electron microscopy, where a pure product is essential.
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What is the storage?
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This product may be stored at ambient temperature. This material is air-sensitive and should be stored under inert gas to preserve product integrity.
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