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Merck

D0730000

Dexpanthenol

European Pharmacopoeia (EP) Reference Standard

Synonim(y):

D-Panthenol, (R)-(+)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide, (R)-2,4-Dihydroxy-3,3-dimethylbutyric 3-hydroxypropylamide, D-Pantothenyl alcohol, Dexpanthenol, Provitamin B

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About This Item

Wzór empiryczny (zapis Hilla):
C9H19NO4
Numer CAS:
Masa cząsteczkowa:
205.25
Beilstein:
1724947
Numer MDL:
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
NACRES:
NA.24

pochodzenie biologiczne

synthetic

klasa czystości

pharmaceutical primary standard

agency

EP Reference Standard

rodzina API

dexpanthenol

Postać

solid

producent / nazwa handlowa

EDQM

metody

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

gęstość

1.20 g/mL at 20 °C (lit.)

Zastosowanie

pharmaceutical (small molecule)

format

neat

temp. przechowywania

2-8°C

ciąg SMILES

CC(C)(CO)[C@@H](O)C(=O)NCCCO

InChI

1S/C9H19NO4/c1-9(2,6-12)7(13)8(14)10-4-3-5-11/h7,11-13H,3-6H2,1-2H3,(H,10,14)/t7-/m0/s1

Klucz InChI

SNPLKNRPJHDVJA-ZETCQYMHSA-N

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Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Dexpanthenol, an alcoholic analog of pantothenic acid, can be potentially applied for skin wound healing application. It is utilized in multi-vitamin formulations, as a parenteral drug and certain cosmetic preparations. When absorbed by the skin, it is transformed into pantothenic acid (vitamin B5), which has implications in the biosynthesis of coenzyme A.

Zastosowanie

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Opakowanie

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Inne uwagi

Sales restrictions may apply.
This page may contain text that has been machine translated.

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


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Certyfikaty analizy (CoA)

Lot/Batch Number

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Anti-inflammatory and anti-oxidative effects of dexpanthenol on lipopolysaccharide induced acute lung injury in mice
Li-Mei W, et al.
Inflammation, 39(5), 1757-1763 (2016)
Simultaneous quantification of dexpanthenol and resorcinol from hair care formulation using liquid chromatography: method development and validation
De, Amit Kumar and Chowdhury, Partha Pratim and Chattapadhyay, Shyamaprasad
Scientifica, 2016(3), 983-988 (2016)
Dexpanthenol
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 2016(3), 2227-2228 (2017)
Simultaneous determination of mepyramine maleate, lidocaine hydrochloride, and dexpanthenol in pharmaceutical preparations by partial least-squares multivariate calibration
Aksu O, et al.
Analytical Letters, 39(4), 751-761 (2006)
Development and validation of reversed phase high performance liquid chromatography method for determination of dexpanthenol in pharmaceutical formulations.
Kulikov U A and Zinchenko A A.
Journal of Pharmaceutical and Biomedical Analysis, 43(3), 983-988 (2007)

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