C1900000

Chlorpromazine hydrochloride

Name: Chlorpromazine hydrochloride
Brand: SIAL
Price: 670 PLN

European Pharmacopoeia (EP) Reference Standard

Synonim(y):

2-Chloro-10-(3-dimethylaminopropyl)phenothiazine hydrochloride, CPZ, Largactil

Slide 1 of 1

Zaloguj się, aby wyświetlić ceny organizacyjne i kontraktowe.

Wybierz wielkość

150 MG

670,00 zł

Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności

Zamów zamówienie zbiorcze

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):

C₁₇H₁₉ClN₂S · HCl

Numer CAS:

69-09-0

Masa cząsteczkowa:

355.33

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329774913

MDL number:

MFCD00012654

Beilstein/REAXYS Number:

3779989

Kluczowe dokumenty

Wyświetl całą dokumentację

Przejdź do

Pomoc techniczna

Potrzebujesz pomocy? Nasz zespół doświadczonych naukowców chętnie Ci pomoże.

Pozwól nam pomóc

InChI

1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H

SMILES string

Cl[H].CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13

InChI key

FBSMERQALIEGJT-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

chlorpromazine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356)

Szukasz podobnych produktów? Odwiedź Przewodnik dotyczący porównywania produktów

Powiązane kategorie

Pharmacopeia & Metrological Institute Standards

Analytical Reference Materials for Pharma QC

Porównaj podobne pozycje

Wyświetl pełne porównanie

Pokaż różnice

1 of 4

Ta pozycja	1125006	31679	BP856
C1900000 Chlorpromazine hydrochloride	USP 1125006 Chlorpromazine hydrochloride	Supelco 31679 Chlorpromazine hydrochloride	BP856 Chlorpromazine hydrochloride
grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade analytical standard	grade pharmaceutical primary standard
manufacturer/tradename EDQM	manufacturer/tradename USP	manufacturer/tradename -	manufacturer/tradename BP
format neat	format neat	format neat	format neat
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) forensics and toxicology pharmaceutical (small molecule)	application(s) pharmaceutical pharmaceutical small molecule
API family chlorpromazine	API family chlorpromazine	API family -	API family chlorpromazine
Gene Information human ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356)	Gene Information human ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356)	Gene Information human ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356)	Gene Information human ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Substitute for benzidine, o-dianisidine, and o-tolidine in the determination of microquantities of hemoglobin and peroxidase.

Biochem/physiol Actions

Chlorpromazine demonstrates cytotoxic and antiproliferative activity against leukemic cells, but does not affect the viability of normal lymphocytes.

Phenothiazine antipsychotic; D₂ dopamine receptor antagonist, H₁ histamine receptor antagonist; inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase and nitric oxide synthase.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Ta strona może zawierać tekst przetłumaczony maszynowo.

related product

Numer produktu

Opis

Cennik

Y0000479

Chlorpromazine impurity D, European Pharmacopoeia (EP) Reference Standard

Y0000507

Chlorpromazine impurity A, European Pharmacopoeia (EP) Reference Standard

Y0000508

Chlorpromazine impurity E, European Pharmacopoeia (EP) Reference Standard

Y0001449

Chlorpromazine impurity F, European Pharmacopoeia (EP) Reference Standard

1125006

Chlorpromazine hydrochloride, United States Pharmacopeia (USP) Reference Standard

BP467

Chlorpromazine sulfoxide, British Pharmacopoeia (BP) Reference Standard

BP856

Chlorpromazine hydrochloride, British Pharmacopoeia (BP) Reference Standard

pictograms

GHS06

signalword

Danger

hcodes

H301,H330

pcodes

P260 - P264 - P270 - P271 - P284 - P304 + P340 + P310

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 3 Oral

Klasa składowania

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Dokumenty section.

Proszę o kontakt, jeśli potrzebna jest pomoc Obsługa Klienta

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Constitutively active 5-HT2/α1 receptors facilitate muscle spasms after human spinal cord injury.

Jessica M D'Amico et al.

Journal of neurophysiology, 109(6), 1473-1484 (2012-12-12)

In animals, the recovery of motoneuron excitability in the months following a complete spinal cord injury is mediated, in part, by increases in constitutive serotonin (5-HT2) and norepinephrine (α1) receptor activity, which facilitates the reactivation of calcium-mediated persistent inward currents

The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting the Akt/mTOR pathway in human U-87MG glioma cells.

Soon Young Shin et al.

Carcinogenesis, 34(9), 2080-2089 (2013-05-22)

2-Chloro-10-[3(-dimethylamino)propyl]phenothiazine mono hydrochloride (chlorpromazine; CPZ) is an antipsychotic agent that was originally developed to control psychotic disorders. The cytotoxic properties of the CPZ are well known, but its mechanism of action is poorly understood. In this study, we investigated the

Molecular cytotoxic mechanisms of chlorpromazine in isolated rat hepatocytes.

Stephanie L MacAllister et al.

Canadian journal of physiology and pharmacology, 91(1), 56-63 (2013-02-02)

Chlorpromazine (CPZ), a member of the largest class of first-generation antipsychotic agents, is known to cause hepatotoxicity in the form of cholestasis and hepatocellular necrosis in some patients. The mechanism of CPZ hepatotoxicity is unclear, but is thought to result

Exposure of chlorpromazine to 266 nm laser beam generates new species with antibacterial properties: contributions to development of a new process for drug discovery.

Mihail Lucian Pascu et al.

PloS one, 8(2), e55767-e55767 (2013-02-14)

Phenothiazines when exposed to white light or to UV radiation undergo a variety of reactions that result in degradation of parental compound and formation of new species. This process is slow and may be sped up with exposure to high

Inhibiting the clathrin-mediated endocytosis pathway rescues K(IR)2.1 downregulation by pentamidine.

Rosanne Varkevisser et al.

Pflugers Archiv : European journal of physiology, 465(2), 247-259 (2012-11-30)

Drug-induced ion channel trafficking disturbance can cause cardiac arrhythmias. We showed that the antiprotozoic pentamidine decreased K(IR)2.x carried I(K1) current and that inhibiting protein degradation in the lysosome increased intracellular K(IR)2.1 levels. In this study, we aim to identify and

Wyświetl wszystkie powiązane dokumenty

Questions

Reviews

No rating value

Active Filters

Nasz zespół naukowców ma doświadczenie we wszystkich obszarach badań, w tym w naukach przyrodniczych, materiałoznawstwie, syntezie chemicznej, chromatografii, analityce i wielu innych dziedzinach.

Skontaktuj się z zespołem ds. pomocy technicznej