EZHFGF21

Human FGF-21 ELISA Kit

measures FGF-21 in 50 μL serum, plasma or cell culture supernatent

• Synonim(y): ELISA Kit for FGF-21, FGF-21 ELISA, Human FGF-21 Detection Kit
• UNSPSC Code: 12161503
• eCl@ss: 32161000
• NACRES: NA.32
• Input: sample type serum; sample type plasma (K2 EDTA); sample type cell culture supernatant
• Species reactivity: human
• Storage temp.: 2-8°C
• Shipped in: wet ice

Właściwości

• Nazwa produktu: Human FGF-21 ELISA Kit, This Human FGF-21 ELISA Kit is used to measure & quantify FGF-21 levels in Metabolism & Inflammation & Immunology research.
• Quality Segment: 200
• species reactivity: human
• packaging: kit of 1 × 96 wells
• parameter: 50 μL sample volume (4hr assay)
• technique(s): ELISA: suitable
• input: sample type serum; sample type plasma (K2 EDTA); sample type cell culture supernatant
• application(s): research use
• assay range: accuracy: 83-99%, standard curve range: 31.3-2000 pg/mL, inter-assay cv: <9%; intra-assay cv: <6%
• detection method: colorimetric (450nm/590nm)
• shipped in: wet ice
• storage temp.: 2-8°C

Opis

General description

Recent studies have demonstrated that fibroblast growth factor 21 (FGF-21), a liver derived protein, is able to increase glucose uptake, as well as lower plasma triglyceride levels in an insulin-independent manner. FGF-21 suppresses glucagon release, thereby increasing insulin sensitivity, and reduces the amount of insulin production required by pancreatic β-cells. Unlike insulin, which works in a rapid, hormone-like manner, FGF-21 activity requires several hours, indicating changes in gene expression. While insulin functions through GLUT4 translocation, FGF-21 has been shown to act primarily through the upregulation of adipocyte GLUT1, a transporter that allows glucose to move from the blood into cells even in the absence of insulin. In addition, no significant weight gain was observed when FGF-21 was injected into animals, and mice that had been genetically engineered to overexpress FGF-21 weighed less and had less adipose tissue than the normal controls.

Application

Research Category
Metabolism

Research Sub Category
Diabetes - Type 2

Metabolic Syndrome

This Human FGF-21 ELISA Kit is used to measure & quantify FGF-21 levels in Metabolism & Inflammation & Immunology research.

This is a 3-hour assay requiring 50 μL of sample.

Used to detect/quantify: FGF-21

Biochem/physiol Actions

No significant cross-reactivity to the cytokines and metabolic hormones tested was observed.

Other Notes

Please contact Technical Service for linearity of dilution.

Disclaimer

For research use only. Not for use in diagnostic procedures.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06,GHS05,GHS09
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H290,H302 + H332,H311,H317,H411
• Ostrzeżenia: P234 - P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Met. Corr. 1 - Skin Sens. 1
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Co się dzieje?: WGK 3