5.30748
SRT1720 HCl
InSolution
Synonim(y):
InSolution SRT1720, HCl, N-(2-(3-(1-piperazynylometylo)imidazo[2,1-b]tiazol-6-ylo)fenylo)-2-chinolinokarboksyamid, 4HCl;, inhibitor acetylotransferazy histonowej XI, inhibitor p300/CBP IX, SRT1720, HCl InSolution, inhibitor HAT XI, inhibitor SIRT3 II, Sirtuin-3 In
Wybierz wielkość
| Do Państwa/SKU | Dostępność | Cena netto |
|---|---|---|
10 mg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 1150,00 zł |
Informacje o tej pozycji
1150,00 zł
Quality Segment
assay
≥98% (HPLC)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles, desiccated (hygroscopic), protect from light
storage temp.
−70°C
SMILES string
[s]1c2[n](c(c1)CN6CCNCC6)cc(n2)c3c(cccc3)NC(=O)c4nc5c(nc4)cccc5.Cl
InChI
1S/C25H23N7OS.ClH/c33-24(22-13-27-20-7-3-4-8-21(20)28-22)29-19-6-2-1-5-18(19)23-15-32-17(16-34-25(32)30-23)14-31-11-9-26-10-12-31;/h1-8,13,15-16,26H,9-12,14H2,(H,29,33);1H
InChI key
DTGRRMPPXCRRIM-UHFFFAOYSA-N
General description
Należy pamiętać, że masa cząsteczkowa tego związku jest zależna od partii ze względu na zmienną zawartość wody.
Biochem/physiol Actions
p300 HAT
SIRT3
Packaging
Physical form
Preparation Note
Other Notes
Minor, R.K., et al. 2011. Sci. Rep.1, 70.
Huber, J.L., et al. 2010. Future Med. Chem.2, 1751.
Pacholec, M., et al. 2010. J. Biol. Chem.285, 8340.
Jin, L., et al. 2009. Protein Sci.18, 514.
Feige, J.N., et al. 2008. Cell Metab.8, 347.
Milne, J.C., et al. 2007. Nature450, 712.
Legal Information
Disclaimer
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Ta pozycja | |||
|---|---|---|---|
| description InSolution | description SRT1720, CAS 925434-55-5, is a cell-permeable inhibitor of the mitochondrial SIRT3. Inhibition is AceCS2-competitive (Ki = 0.56 µM; Km = 2.44 µM), but NAD+-uncompetitive (Ki = 0.34 µM; Km = 280 µM). | description The SIRT2 Inhibitor, AGK2, also referenced under CAS 304896-28-4, controls the biological activity of SIRT2. This small molecule/inhibitor is primarily used for Cell Structure applications. | description InSolution |
| assay ≥98% (HPLC) | assay ≥97% (HPLC) | assay ≥95% (HPLC) | assay ≥97% (HPLC) |
| form liquid | form solid | form solid | form liquid |
| manufacturer/tradename Calbiochem® | manufacturer/tradename Calbiochem® | manufacturer/tradename Calbiochem® | manufacturer/tradename Calbiochem® |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −70°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| storage condition OK to freeze, desiccated (hygroscopic), avoid repeated freeze/thaw cycles, protect from light | storage condition OK to freeze, protect from light | storage condition OK to freeze, protect from light | storage condition OK to freeze, desiccated (hygroscopic), protect from light |
Klasa składowania
10 - Combustible liquids
wgk
WGK 3
flash_point_f
188.6 °F
flash_point_c
87 °C
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