Kluczowe dokumenty

Wyświetl całą dokumentację

Przejdź do

345887

Ginkgolic Acid (15:1)

Name: Ginkgolic Acid (15:1)
Brand: MM
Price: 1330 PLN
Availability: InStock

A cell-permeable anacardic acid analog that inhibits protein SUMO .

Synonim(y):

Ginkgolic Acid (15:1), (Z)-6-(Pentadec-8-enyl)-2-hydroxybenzoic acid, Histone Acetyltransferase Inhibitor VI, PCAF Inhibitor II, SUMOylation Inhibitor, HAT Inhibitor VI, Histone Acetyltransferase Inhibitor VI, PCAF Inhibitor II, SUMOylation Inhibitor, (Z)-6-(Pentadec-8-enyl)-2-hydroxybenzoic acid, HAT Inhibitor VI

Zaloguj się, aby wyświetlić ceny organizacyjne i kontraktowe.

Wybierz wielkość

Zmień widok

Do Państwa/SKU	Dostępność	Cena netto
5 mg	Przewidywany termin wysyłki07 września 2026zKuehne + Nagel Sp. z o.o.	1330,00 zł

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):

C₂₂H₃₄O₃

Numer CAS:

22910-60-7

Masa cząsteczkowa:

346.50

UNSPSC Code:

12352106

NACRES:

NA.77

MDL number:

MFCD03093717

Assay:

≥98% (HPLC)

Form:

solid

Storage condition:

OK to freeze, protect from light

1330,00 zł

Przewidywany termin wysyłki07 września 2026Szczegóły

Pomoc techniczna

Potrzebujesz pomocy? Nasz zespół doświadczonych naukowców chętnie Ci pomoże.

Pozwól nam pomóc

Właściwości

Quality Segment

100

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

color

white

solubility

DMSO: 100 mg/mL, ethanol: 100 mg/mL

shipped in

ambient

storage temp.

−20°C

SMILES string

Oc1c(c(ccc1)CCCCCCC\C=C/CCCCCC)C(=O)O

InChI

1S/C22H34O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-17-15-18-20(23)21(19)22(24)25/h7-8,15,17-18,23H,2-6,9-14,16H2,1H3,(H,24,25)/b8-7-

InChI key

YXHVCZZLWZYHSA-FPLPWBNLSA-N

Opis

General description

A cell-permeable anacardic acid (Cat. No. 172050) analog that inhibits protein SUMO modification (IC₅₀ = 3.0 µM using RanGAP1-C2 as substrate) in an ATP-dependent manner by selectively targeting SUMO-activating enzyme E1 and interfering with E1-SUMO intermediate formation independent of E1 active site cysteine. Both ginkgolic acid and anacardic acid are shown to effectively decrease overall SUMOylation of 293T cellular proteins, including p53, in a dose-dependent manner, while neither compound is effective in affecting overall cellular protein ubiquitination or histone H4K8 acetylation in 293T cultures, although both compounds are shown to inhibit histone lysine acetylation by PCAF in cell-free acetylase assays. Also available as a 25 mM solution in DMSO (Cat. No. 5.08197).

Packaging

Packaged under inert gas

Preparation Note

Following intitial thaw, aliquot and freeze (-20°C).

Other Notes

Fukuda, I., et al. 2009. Chem. Biol.16, 133.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

Ta strona może zawierać tekst przetłumaczony maszynowo.

Porównaj podobne pozycje

Wyświetl pełne porównanie

Pokaż różnice

1 of 1

Ta pozycja	172050	239802	658401
Sigma-Aldrich 345887 Ginkgolic Acid (15:1)	Sigma-Aldrich 172050 Kwas anakardowy	Sigma-Aldrich 239802 Curcumin, Curcuma longa L.	Sigma-Aldrich 658401 AG 490
description A cell-permeable anacardic acid analog that inhibits protein SUMO .	description The Anacardic Acid, also referenced under CAS 16611-84-0, modulates the biological activity of Anacardic. This small molecule/inhibitor is primarily used for Cell Structure applications.	description A cell-permeable and irreversible antitumor and anti-inflammatory agent that acts as an inhibitor of 5-lipoxygenase (IC₅₀ = 8 µM) and cyclooxygenase (IC₅₀ = 52 µM).	description A cell-permeable, reversible, substrate competitive, and potent inhibitor of epidermal growth factor receptor kinase autophosphorylation (IC₅₀ = 100 nM).
assay ≥98% (HPLC)	assay ≥95% (HPLC)	assay ≥80% (HPLC)	assay ≥98% (HPLC)
form solid	form solid	form solid	form solid
manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
storage temp. −20°C	storage temp. 2-8°C	storage temp. 10-30°C	storage temp. −20°C
solubility ethanol: 100 mg/mL, DMSO: 100 mg/mL	solubility methanol: 10 mg/mL, DMSO: 10 mg/mL	solubility DMSO: 5 mg/mL, acetic acid: 10 mg/mL	solubility DMSO: 100 mg/mL

Still not finding the right product?

Explore all of our products under Ginkgolic Acid (15:1)

pictograms

GHS07

signalword

Warning

hcodes

H317,H413

pcodes

P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313

Hazard Classifications

Aquatic Chronic 4 - Skin Sens. 1

Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

509.9 °F - (calculated)

flash_point_c

265.5 °C - (calculated)

Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Dokumenty section.

Proszę o kontakt, jeśli potrzebna jest pomoc Obsługa Klienta

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.