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178468

Apolipoproteina E, ludzkie osocze, lipoproteiny o bardzo niskiej gęstości

Native apolipoprotein E from human plasma. A major component of VLDL and IDL. Serves as a major cholesterol carrier. Essential for the normal catabolism of triglyceride-rich lipoprotein constituents.

Synonim(y):

Apo E

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Rozmiar/SKUDostępnośćCena netto
50 μg
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
1940,00 zł

Informacje o tej pozycji

NACRES:
NA.25
UNSPSC Code:
12352202
Form:
liquid
Assay:
≥95% (SDS-PAGE)

1940,00 zł


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Quality Segment

assay

≥95% (SDS-PAGE)

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

shipped in

wet ice

storage temp.

−20°C

General description

Native apolipoprotein E from human plasma. A component of VLDL and of a subclass of HDL. Present in normal plasma at concentrations of 50 µg/ml. Serves as a ligand for LDL receptors, where it participates in the transport and redistribution of cholesterol and other lipids. Also functions in immunoregulation and cell growth differentiation. Inhibits mitogen-induced T-lymphocyte proliferation and modulation of smooth muscle cell differentiation.

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In 50 mM NH₄HCO₃, pH 8.0.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Other Notes

Kelly, M.E., et al. 1994. Cell Immunol. 159, 124.
Mahley, R.W. 1988. Science 240, 622.
Rall, S.C., et al. 1986. Methods Enzymol. 128, 273.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Toxicity: Standard Handling (A)
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178455178452ALP30
description

Native apolipoprotein E from human plasma. A major component of VLDL and IDL. Serves as a major cholesterol carrier. Essential for the normal catabolism of triglyceride-rich lipoprotein constituents.

description

Native apolipoprotein A-II from human plasma. The second most abundant protein of HDL. Binds to phospholipids during lipoprotein metabolism. Displaces LCAT bound to lipoprotein.

description

Native apolipoprotein A-I from human plasma. Functions as a cofactor for lecithin-cholesterol acyltransferase. A component of high density lipoprotein.

description

-

assay

≥95% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

assay

>95% (SDS-PAGE)

form

liquid

form

liquid

form

liquid

form

solid

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-10 to -25°C

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

storage condition

avoid repeated freeze/thaw cycles, OK to freeze

storage condition

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100


Klasa składowania

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Certyfikaty analizy (CoA)

Lot/Batch Number

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Questions

  1. is there lipid associated with this protein?

    1 answer
    1. During the purification process for Apolipoprotein E, lipids are removed as part of the procedure. As a result, the final product is not expected to contain associated lipids.

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