178468

Apolipoproteina E, ludzkie osocze, lipoproteiny o bardzo niskiej gęstości

Native apolipoprotein E from human plasma. A major component of VLDL and IDL. Serves as a major cholesterol carrier. Essential for the normal catabolism of triglyceride-rich lipoprotein constituents.

• Synonim(y): Apo E
• Kod UNSPSC: 12352202
• NACRES: NA.25

Właściwości

• Poziom jakości: 100
• Próba: ≥95% (SDS-PAGE)
• Formularz: liquid
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze; avoid repeated freeze/thaw cycles
• Warunki transportu: wet ice
• temp. przechowywania: −20°C

Opis

Opis ogólny

Native apolipoprotein E from human plasma. A component of VLDL and of a subclass of HDL. Present in normal plasma at concentrations of 50 µg/ml. Serves as a ligand for LDL receptors, where it participates in the transport and redistribution of cholesterol and other lipids. Also functions in immunoregulation and cell growth differentiation. Inhibits mitogen-induced T-lymphocyte proliferation and modulation of smooth muscle cell differentiation.

Opakowanie

Please refer to vial label for lot-specific concentration.

Ostrzeżenie

Toxicity: Standard Handling (A)

Postać fizyczna

In 50 mM NH₄HCO₃, pH 8.0.

Uwaga dotycząca przygotowania

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Rekonstytucja

Following initial thaw, aliquot and freeze (-20°C).

Inne uwagi

Kelly, M.E., et al. 1994. Cell Immunol. 159, 124.
Mahley, R.W. 1988. Science 240, 622.
Rall, S.C., et al. 1986. Methods Enzymol. 128, 273.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Oświadczenie o zrzeczeniu się odpowiedzialności

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable