1.05995

(-)-Menthol

EMPROVE^® ESSENTIAL, Ph. Eur., BP, JP, USP

• Synonim(y): (-)-Menthol, 2-Isopropyl-5-methylcyclohexanol
• Wzór empiryczny (zapis Hilla): C₁₀H₂₀O
• Numer CAS: 2216-51-5
• Masa cząsteczkowa: 156.27
• UNSPSC Code: 12352104
• EC Index Number: 218-690-9
• MDL number: MFCD00062979

Właściwości

• Quality Segment: 500
• agency: BP, JP, Ph. Eur., USP
• description: EMPROVE^® ESSENTIAL Ph Eur,BP,JP,USP
• product line: EMPROVE^® ESSENTIAL
• form: solid
• potency: 3300 mg/kg LD₅₀, oral (Rat), >5000 mg/kg LD₅₀, skin (Rabbit)
• bp: 216 °C/1013 hPa
• mp: 41-44 °C
• transition temp: flash point 101 °C
• solubility: 490 mg/L
• density: 0.890 g/cm³ at 20 °C
• application(s): pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 15-25°C
• SMILES string: O[C@H]1[C@@H](CC[C@H](C1)C)C(C)C
• InChI: 1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10-/m1/s1
• InChI key: NOOLISFMXDJSKH-KXUCPTDWSA-N

Opis

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Menthol is a commonly used ingredient in food and pharmaceutical applications. In pharmaceutical applications, menthol has been used primarily for oral dosage forms.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319
• pcodes: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: 201.2 °F - closed cup
• flash_point_c: 94 °C - closed cup