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189901

Methylmagnesium chloride solution

3.0 M in THF

Synonim(y):

Chloromethylmagnesium, Methyl magnesium chloride, Methylmagnesiumchloride

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Rozmiar/SKUDostępnośćCena netto
100 mL
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371,00 zł
4 x 25 mL
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424,00 zł
800 mL
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1430,00 zł
8 L
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6360,00 zł

Informacje o tej pozycji

Wzór liniowy:
CH3MgCl
Numer CAS:
Masa cząsteczkowa:
74.79
UNSPSC Code:
12352103
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3587199
Concentration:
3.0 M in THF
Form:
liquid

371,00 zł


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form

liquid

Quality Segment

autoignition temp.

609 °F

reaction suitability

reaction type: Grignard Reaction

packaging

Kilo-Lab™ of , Sure/Seal™ of

concentration

3.0 M in THF

density

1.013 g/mL at 25 °C

SMILES string

C[Mg]Cl

InChI

1S/CH3.ClH.Mg/h1H3;1H;/q;;+1/p-1

InChI key

RQNMYNYHBQQZSP-UHFFFAOYSA-M

Application

Methylmagnesium chloride solution (3 M in THF) undergoes 1,3-addition with dialdose derived nitrones to form N-benzylhydroxylamines. The reductive cleavage of the N-O bond of these N-benzylhydroxylamines results in N-benzylaminosugars, which are key moieties of bioactive compounds. It can also react with Garner type aldehydes to form the corresponding secondary alcohols.

Packaging

The 25 mL Sure/Seal™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Legal Information

Kilo-Lab is a trademark of Merck KGaA, Darmstadt, Germany
Sure/Seal is a trademark of Sigma-Aldrich Co. LLC
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Ta pozycja
224375424056
description

3.0 M in THF

description

2.0 M in diethyl ether

description

0.5 M in diethyl ether

concentration

3.0 M in THF

concentration

2.0 M in diethyl ether

concentration

0.5 M in diethyl ether

Quality Level

200

Quality Level

100

Quality Level

100

form

liquid

form

-

form

-

density

1.013 g/mL at 25 °C

density

0.828 g/mL at 25 °C

density

0.793 g/mL at 25 °C

reaction suitability

reaction type: Grignard Reaction

reaction suitability

reaction type: Grignard Reaction

reaction suitability

reaction type: Grignard Reaction

packaging

Sure/Seal™ of , Kilo-Lab™ of

packaging

Sure/Seal™ of

packaging

Sure/Seal™ of


Słowo ostrzegawcze

Danger

Narządy docelowe

Central nervous system, Respiratory system

supp_hazards

Klasa składowania

4.3 - Hazardous materials which set free flammable gases upon contact with water

Temperatura zapłonu (°F)

1.0 °F - closed cup

Temperatura zapłonu (°C)

-17.2 °C - closed cup

PPE (środki ochrony indywidualnej)

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Hazard Classifications

Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3 - Water-react. 1


Wykazy regulacyjne

Wykazy regulacyjne dotyczą głównie produktów chemicznych. Można w nich podawać ograniczoną liczbę informacji na temat produktów niechemicznych. Brak wpisu oznacza, że żaden ze składników nie znajduje się w wykazie. Użytkownik odpowiada za zagwarantowanie bezpiecznego i zgodnego z prawem stosowania produktu.

109-99-9 + 676-58-4

CAS No.


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Certyfikaty analizy (CoA)

Lot/Batch Number

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Questions

1–8 of 8 Questions  
  1. Art der Verpackung der 8L-Gebinde?

    1 answer
    1. The 8 L quantity of this product is packaged in an 18 L carbon-steel Kilo-Lab™ cylinder that conforms to specification 4BA240.

      Further details are available in the Kilo-Lab™ Cylinder Technical Bulletin:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/866/791/al_techbull_al235.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  3. Should I store the product under inert conditions?

    1 answer
    1. This product is packaged in Sure/Seal bottles and closures in order to preserve the quality of the reagent. Exposure to air and light may result in degradation. To maintain the shelf life and quality, larger package sizes may be stored in aliquots using smaller Sure/Seal bottles and Crown caps. Please see the link below to review these product options:
      Crown Caps - for Sure/Seal bottles
      https://www.sigmaaldrich.com/product/aldrich/z102148
      Sure/Seal bottles
      https://www.sigmaaldrich.com/substance/suresealbottles1234598765

      Helpful?

  4. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  5. In one litere of tetra hydra furan THF, how much of methyl megnesium chloride should be requried?

    1 answer
    1. The molar mass of methylmagnesium chloride is 74.79 g/mol. This product is a 3.0 M methylmagnesium chloride solution in THF. This corresponds to 224.37 grams of methylmagnesium chloride per liter of THF to achieve this concentration.

      Helpful?

  6. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  7. Is the BHT inhibitor present in Product 189901, Methylmagnesium chloride solution?

    1 answer
    1. Yes, BHT is present in the THF. This information can be found on the MSDS, which is available from our website.

      Helpful?

  8. Can Product 189901, Methylmagnesium chloride solution, be used if a precipitate is present?

    1 answer
    1. If a precipitate is present, the product can be heated and stirred until the precipitate is dissolved.

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