SIRPA
signal-regulatory protein alpha
Synonimy:
BIT, CD172A, MFR, MYD-1, P84, PTPNS1, SHPS1, SIRP
Gatunek:
Human SIRPA (140885), Mouse Sirpa (19261), Rat Sirpa (25528), naked mole-rat Sirpa (101706086), dog SIRPA (609452), domestic cat SIRPA (101084787), Horse SIRPA (100067339), Domestic Rabbit SIRPA (100351485), sheep SIRPA (101105677), domestic guinea pig Sirpa (100719630) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(140885) Summary: The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq, Jul 2008]
- Mouse(19261) signal-regulatory protein alpha
- Rat(25528) signal-regulatory protein alpha
- naked mole-rat(101706086) signal-regulatory protein alpha
- dog(609452) signal-regulatory protein alpha
- domestic cat(101084787) signal-regulatory protein alpha
- Horse(100067339) signal-regulatory protein alpha
- Domestic Rabbit(100351485) signal-regulatory protein alpha
- sheep(101105677) signal-regulatory protein alpha
- domestic guinea pig(100719630) signal-regulatory protein alpha
- cow(327666) signal-regulatory protein alpha
- chicken(419267) signal-regulatory protein alpha
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Macrophages/Granulocytes Antibody, clone OX-41, clone OX-41, Chemicon®, from mouse,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Monoclonal Anti-PTPNS1 antibody produced in mouse, clone 1D10, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
western blot
Anti-SIRPA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-SIRPA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-SIRPA Antibody, clone 3N8 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, monkey
Zastosowanie
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot