PSMC5
proteasome (prosome, macropain) 26S subunit, ATPase, 5
Synonimy:
S8, SUG-1, SUG1, TBP10, TRIP1, p45, p45/SUG
Gatunek:
Human PSMC5 (5705), Mouse Psmc5 (19184), Rat Psmc5 (81827), Zebrafish psmc5 (445285), chicken PSMC5 (428274), domestic guinea pig Psmc5 (100717173), naked mole-rat Psmc5 (101710432), sheep PSMC5 (101104076), cow PSMC5 (282015), Horse PSMC5 (100053987) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(5705) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
- Mouse(19184) protease (prosome, macropain) 26S subunit, ATPase 5
- Rat(81827) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- Zebrafish(445285) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- chicken(428274) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- domestic guinea pig(100717173) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- naked mole-rat(101710432) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- sheep(101104076) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- cow(282015) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- Horse(100053987) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- domestic cat(101097360) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- dog(480478) proteasome (prosome, macropain) 26S subunit, ATPase, 5
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti PSMC5 Antibody, clone 24GB1500, Rabbit Monoclonal, clone 24GB1500, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human, rat
Zastosowanie
flow cytometry
western blot
western blot
Anti-PSMC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anty-PSMC5, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
immunohistochemistry