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Merck

PDE1A

phosphodiesterase 1A, calmodulin-dependent

Synonimy:
CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5136) Summary: Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]
  • Mouse(18573) phosphodiesterase 1A, calmodulin-dependent
  • Rat(81529) phosphodiesterase 1A, calmodulin-dependent
  • chicken(424116) phosphodiesterase 1A, calmodulin-dependent
  • Zebrafish(564465) phosphodiesterase 1A, calmodulin-dependent
  • domestic cat(101083101) phosphodiesterase 1A, calmodulin-dependent
  • dog(403652) phosphodiesterase 1A, calmodulin-dependent
  • naked mole-rat(101712147) phosphodiesterase 1A, calmodulin-dependent
  • sheep(101119369) phosphodiesterase 1A, calmodulin-dependent
  • Domestic Rabbit(100346878) phosphodiesterase 1A, calmodulin-dependent
  • cow(281969) phosphodiesterase 1A, calmodulin-dependent
  • Horse(100054082) phosphodiesterase 1A, calmodulin-dependent
  • domestic guinea pig(100527956) phosphodiesterase 1A, calmodulin-dependent

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PDE1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Anti-PDE1A antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse
Zastosowanie
western blot
Anti-PDE1A antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
8-Methoxymethyl-3-isobutyl-1-methylxanthine, ≥98%,
Gatunek
human
Vinpocetine, ≥98%, solid,
Gatunek
human
Dipyridamole, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
Dipyridamole impurity standard, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
Dipyridamole, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
PDE1A Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Pde1a,
Gatunek
mouse
MISSION® esiRNA, targeting human PDE1A,
Gatunek
human