Przejdź do zawartości
Merck

MARCH4

membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase

Synonimy:
MARCH-IV, RNF174
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(57574) Summary: MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]
  • Mouse(381270) membrane-associated ring finger (C3HC4) 4
  • Rat(367295) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • sheep(101107500) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • Zebrafish(562065) membrane-associated ring finger (C3HC4) 4
  • Horse(100050538) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • cow(527624) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • dog(488515) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • naked mole-rat(101718651) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • domestic guinea pig(100725253) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • domestic cat(101082766) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-MARCH4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human MARCH4,
Gatunek
human