LPIN3
lipin 3
Synonimy:
LIPN3L, SMP2, dJ450M14.2, dJ450M14.3, dJ620E11.2
Gatunek:
Human LPIN3 (64900), Mouse Lpin3 (64899), Rat Lpin3 (362261), dog LPIN3 (485876), chicken LPIN3 (101751036), chicken LPIN3 (101669703), cow LPIN3 (521637), domestic cat LPIN3 (101096222), naked mole-rat Lpin3 (101722006), sheep LPIN3 (101106450) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(64900) Summary: Humans lipodystrophy is characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Mice carrying mutations in the fatty liver dystrophy (fld) gene have similar phenotypes. Through positional cloning, the mouse gene responsible for fatty liver dystrophy was isolated and designated Lpin1. The nuclear protein encoded by Lpin1 was named lipin. Lpin1 mRNA was expressed at high levels in adipose tissue and was induced during differentiation of preadipocytes. These results indicated that lipin is required for normal adipose tissue development and provided a candidate gene for human lipodystrophy. Through database searches, mouse and human EST and genomic sequences with similarities to Lpin1 were identified. These included two related mouse genes (Lpin2 and Lpin3) and three human homologs (LPIN1, LPIN2, and LPIN3). Human LPIN1 gene has been mapped to 2p25.; linkages of fat mass and serum leptin levels to this same region have been noted. Human LPIN2 and LPIN3 mapped to chromosomes 18p11 and 20q11-q12, respectively. The mouse genes encoding Lpin1, Lpin2, and Lpin3 mapped to chromosome 12, 17, and 2, respectively. [provided by RefSeq, Jul 2008]
- Mouse(64899) lipin 3
- Rat(362261) lipin 3
- dog(485876) lipin 3
- chicken(101751036) lipin 3
- chicken(101669703) lipin 3
- cow(521637) lipin 3
- domestic cat(101096222) lipin 3
- naked mole-rat(101722006) lipin 3
- sheep(101106450) lipin 3
- Horse(100055753) lipin 3
- domestic guinea pig(100733777) lipin 3
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anty-LPIN3, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-LPIN3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
esiRNA
Numer produktu
Opis
Gatunek