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Merck

IL5RA

interleukin 5 receptor, alpha

Synonimy:
CD125, CDw125, HSIL5R3, IL5R
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(3568) Summary: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011]
  • Mouse(16192) interleukin 5 receptor, alpha
  • Rat(114103) interleukin 5 receptor, alpha
  • chicken(771801) interleukin 5 receptor, alpha
  • dog(476553) interleukin 5 receptor, alpha
  • domestic cat(101099031) interleukin 5 receptor, alpha
  • naked mole-rat(101701153) interleukin 5 receptor, alpha
  • sheep(101111837) interleukin 5 receptor, alpha
  • domestic guinea pig(100379257) interleukin 5 receptor, alpha
  • cow(615848) interleukin 5 receptor, alpha

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human IL-5 R α ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-IL5RA antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human IL5RA,
Gatunek
human