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IDH2

isocitrate dehydrogenase 2 (NADP+), mitochondrial

Synonimy:
D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(3418) Summary: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. [provided by RefSeq, Jul 2008]
  • Mouse(269951) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • Rat(361596) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • Thale Cress(816218) Isocitrate dehydrogenase [NAD] regulatory subunit 2
  • Zebrafish(386951) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • dog(479043) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • chicken(431056) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • Domestic Rabbit(100340796) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • sheep(101102843) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • cow(327669) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • domestic cat(101082315) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • naked mole-rat(101708667) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • domestic guinea pig(100726681) isocitrate dehydrogenase 2 (NADP+), mitochondrial

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-IDH2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
bovine, canine, human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot
Monoclonal Anti-IDH2 antibody produced in mouse, clone 5F11, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry

western blot
Anti-IDH2 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
western blot
Anti-IDH2 antibody produced in rabbit, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Anti-IDH2 antibody produced in rabbit, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot

Kits

Numer produktu
Opis
Gatunek
IDH Activity Assay Kit, sufficient for 100 colorimetric tests,
Gatunek
mouse, rat, human

Proteins

Numer produktu
Opis
Gatunek
IDH2, FLAG® -Tag, recombinant, expressed in baculovirus infected Sf9 cells,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human IDH2,
Gatunek
human
MISSION® esiRNA, targeting mouse Idh2,
Gatunek
mouse